Evidence map›Paper›PMID 31086616›Full record

ArticleThe Pan African medical journal2018

Age at diagnosis predicted survival outcome of female patients with breast cancer at a tertiary hospital in Yogyakarta, Indonesia.

Evi Susanti Sinaga, Riris Andono Ahmad, Siddharudha Shivalli, Susanna Hilda Hutajulu

Registry-linked trialAbstract read
In one paragraph

Article in The Pan African medical journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05570266 (Genetic and Non-Genetic Breast Cancer Risk Prediction Evaluation in Indonesian Samples), which is not on this map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05570266 completednot on this mapstarted 2020, after this paper: background citation

Genetic and Non-Genetic Breast Cancer Risk Prediction Evaluation in Indonesian Samples

Typeobservational_patient_registrySponsorNalagenetics Pte LtdRan2020 to 2023Enrolled322ConditionsBreast CancerArmsBreast Cancer Risk Prediction Software
3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Evi Susanti SinagaDepartment of Community Medicine/Public Health, Faculty of Medicine, Trisakti University, Jakarta, Indonesia.
Riris Andono AhmadDepartment of Biostatistics, Epidemiology and Population Health, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia.
Siddharudha ShivalliDepartment of Public Heath, Yenepoya Medical College, Yenepoya University, Mangalore, Karnataka, India.
Susanna Hilda HutajuluDivision of Hematology and Medical Oncology, Department of Internal Medicine, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada/Dr Sardjito General Hospital, Yogyakarta, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionBreast cancer is the most common cancer in women in Indonesia. Patients' survival depends on various factors, namely patient-, tumor-, and treatment-related factors. Survival analysis on Indonesian patients has only been reported in a few studies. This study aimed to identify the factors that are associated with five-year overall survival (OS) among patients with breast cancer at a local tertiary hospital in Indonesia.

methodsA retrospective cohort study was conducted at Dr Sardjito Hospital, Yogyakarta. Female patients diagnosed with breast cancer between January and December 2009 were studied. Socio-demographic and clinicopathological data were collected from the medical and pathological records. The five-year OS rate was assessed using Kaplan Meier method and prognostic factors were analyzed using Cox regression.

resultsA total of 213 eligible patients with breast cancer were recruited. The five-year OS probability of the breast cancer patient was 51.07%. The majority of the patients (151, 70.9%) presented an advanced stage at the time of diagnosis. In the bi-variable analysis, cases who were younger, of a lower educational status, at a more advanced stage, with a bigger tumor size, and a central tumor location showed a worse five-year OS compared to their counterparts (p = 0.005, 0.001, 0.004, 0.011 and 0.023, respectively). In the multivariable analysis, age was an independent predictor for the OS (HR = 3.73; 95% CI = 1.0-13.6, p = 0.046).

conclusionThe five-year OS of breast cancer patients in the local tertiary hospital was 51.07%. The patients' age at diagnosis was the only significant prognostic factor for the patients' survival.

Indexed as

Age FactorsBreast NeoplasmsCohort StudiesEducational StatusFemaleHumansIndonesiaKaplan-Meier EstimateMiddle AgedMultivariate AnalysisNeoplasm StagingPrognosisRetrospective StudiesSurvival RateTertiary Care CentersageBreast cancerfive-year overall survivalIndonesia

Identifiers

PMID31086616
PMCPMC6492206

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Registered trials

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