Evidence map›Paper›PMID 31086604›Full record

ArticleExperimental and therapeutic medicine2019

Long non-coding RNA BLACAT1 promotes the proliferation and invasion of glioma cells via Wnt/β-catenin signaling.

Xiushan Li, Shujing Qi, Dongzhou Ma, Jinbiao Fan, Jingtao Wang

Abstract read
In one paragraph

Article in Experimental and therapeutic medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
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  4. Article
  5. Review
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  7. Article
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  9. Article
  10. Long Non-Coding RNA BLACAT1 in Human Cancers.OncoTargets and therapy · 2020
    Review
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xiushan LiDepartment of Neurosurgery, Affiliated Hospital of Hebei University of Engineering, Handan, Hebei 056002, P.R. China.
Shujing QiDepartment of Nutrition, Affiliated Hospital of Hebei University of Engineering, Handan, Hebei 056002, P.R. China.
Dongzhou MaDepartment of Neurosurgery, Affiliated Hospital of Hebei University of Engineering, Handan, Hebei 056002, P.R. China.
Jinbiao FanDepartment of Neurosurgery, Affiliated Hospital of Hebei University of Engineering, Handan, Hebei 056002, P.R. China.
Jingtao WangDepartment of Neurosurgery, Affiliated Hospital of Hebei University of Engineering, Handan, Hebei 056002, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Long non-coding RNAs (lncRNAs) are hypothesized to regulate numerous biological behaviors in human cancers. The present study aimed to explore the roles of lncRNA bladder cancer associated transcript 1 (BLACAT1) in glioma. The expression of BLACAT1 in glioma tissues and cell lines was determined by reverse transcription-quantitative polymerase chain reaction (RT-qPCR). CCK-8 assay, colony formation assay, wound healing assay and Transwell invasion assay were used to explore the roles of BLACAT1 in glioma cells. RT-qPCR and western blot analysis were used to determine the BLACAT1 molecular mechanism. The findings demonstrated that lncRNA BLACAT1 was overexpressed in glioma tissues and cell lines. High BLACAT1 expression was correlated with high tumor grade in glioma patients. Functional assays determined that BLACAT1 promoted glioma cell proliferation, migration, invasion and epithelial-mesenchymal transition

Indexed as

bladder cancer associated transcript 1epithelial-mesenchymal transitiongliomainvasionlong non-coding RNAproliferationWnt/β-catenin

Identifiers

PMID31086604
PMCPMC6489056

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.