ArticleNature methods2019
Bioluminescent-based imaging and quantification of glucose uptake in vivo.
Article in Nature methods, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed.
- Enzyme-Activated MRI for In Vivo Glucose Imaging via a Biodegradable Chromium Nanoprobe.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Click-to-Release Reactions for Tertiary Amines and Pyridines.Journal of the American Chemical Society · 2026Article
- A novel inherent fluorescence biodegradable polyurethane.Regenerative biomaterials · 2026Article
- Real-Time Tracking of ASCT2-Mediated Glutamine Uptake in Living Tumors With a Bioorthogonal Bioluminescent Probe.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Review
- A feeding-induced myokine modulates glucose homeostasis.Nature metabolism · 2025Article
- Post-click labeling enables highly accurate single cell analyses of glucose uptake ex vivo and in vivo.Communications biology · 2024Article
- The transcription factor ChREBP Orchestrates liver carcinogenesis by coordinating the PI3K/AKT signaling and cancer metabolism.Nature communications · 2024Article
- A Comprehensive Exploration of Bioluminescence Systems, Mechanisms, and Advanced Assays for Versatile Applications.Biochemistry research international · 2024Review
- Solid-Phase Synthesis of Caged Luminescent Peptides via Side Chain Anchoring.Bioconjugate chemistry · 2023Article
- Recent Advances in Bioorthogonal Ligation and Bioconjugation.Topics in current chemistry (Cham) · 2023Review
- In vivo bioluminescence imaging of natural bacteria within deep tissues via ATP-binding cassette sugar transporter.Nature communications · 2023Article
- A Sequential Electrospinning of a Coaxial and Blending Process for Creating Double-Layer Hybrid Films to Sense Glucose.Sensors (Basel, Switzerland) · 2023Article
- Facile preparation of FeRoyal Society open science · 2022Article
- Evaluation of Biological Activity of Natural Compounds: Current Trends and Methods.Molecules (Basel, Switzerland) · 2022Review
- RuOMikrochimica acta · 2022Article
- Genetic evidence that uptake of the fluorescent analog 2NBDG occurs independently of known glucose transporters.PloS one · 2022Article
- Advancing Tumor Microenvironment Research by Combining Organs-on-Chips and Biosensors.Advances in experimental medicine and biology · 2022Review
- Bioorthogonal Reactions of Triarylphosphines and Related Analogues.Chemical reviews · 2021Review
- Portable bioluminescent platform for in vivo monitoring of biological processes in non-transgenic animals.Nature communications · 2021Article
Corrections and comments
- Commented on byElena Goun.2019
Authors and funding
12 authors.
Funding
Abstract
Glucose is a major source of energy for most living organisms, and its aberrant uptake is linked to many pathological conditions. However, our understanding of disease-associated glucose flux is limited owing to the lack of robust tools. To date, positron-emission tomography imaging remains the gold standard for measuring glucose uptake, and no optical tools exist for non-invasive longitudinal imaging of this important metabolite in in vivo settings. Here, we report the development of a bioluminescent glucose-uptake probe for real-time, non-invasive longitudinal imaging of glucose absorption both in vitro and in vivo. In addition, we demonstrate that the sensitivity of our method is comparable with that of commonly used
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.