Observational studyPediatric research2019
Heart rate fluctuation after birth predicts subsequent cardiorespiratory stability in preterm infants.
Observational study in Pediatric research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07324941 (The Role of Electroencephalography Evaluation in Caffeine Discontinuation Timing in Premature Infants), which is not on this map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Role of Electroencephalography Evaluation in Caffeine Discontinuation Timing in Premature Infants
Who cites it
10 citing papers in PubMed, 13 citations in OpenAlex.
- Radar-Based Monitoring: A Proof of Principle Study in a Piglet Model for a Novel Approach in Non-Contact Vital Sign Monitoring.Sensors (Basel, Switzerland) · 2026Article
- Future perspectives of heart rate and oxygenation monitoring in the neonatal intensive care unit - a narrative review.Journal of clinical monitoring and computing · 2025Review
- Sample entropy of oxygen saturation in preterm infants.Scientific reports · 2025Article
- Association of Heart Rate Variability with Postnatal Maturation in Preterm Infants.Neonatology · 2025Article
- Sample entropy correlates with intraventricular hemorrhage and mortality in premature infants early in life.Pediatric research · 2024Article
- Bradycardia May Decrease Cardiorespiratory Coupling in Preterm Infants.Entropy (Basel, Switzerland) · 2023Article
- Comparison of oxygen supplementation in very preterm infants: Variations of oxygen saturation features and their application to hypoxemic episode based risk stratification.Frontiers in pediatrics · 2023Article
- Novel approaches to capturing and using continuous cardiorespiratory physiological data in hospitalized children.Pediatric research · 2023Review
- The rhythm of a preterm neonate's life: ultradian oscillations of heart rate, body temperature and sleep cycles.Journal of pharmacokinetics and pharmacodynamics · 2021Observational
- Caffeine preserves quiet sleep in preterm neonates.Pharmacology research & perspectives · 2020Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCardiorespiratory stability of preterm infants is a prerequisite for discharge from the neonatal intensive care unit (NICU) but very difficult to predict. We aimed to assess whether characterizing heart rate fluctuation (HRF) within the first days of life has prognostic utility.
methodsWe conducted a prospective cohort study in 90 preterm infants using a previously validated surface diaphragmatic electromyography (sEMG) method to derive interbeat intervals. We characterized HRF by time series parameters including sample entropy (SampEn) and scaling exponent alpha (ScalExp) obtained from daily 3-h measurements. Data were analyzed by multivariable, multilevel linear regression.
resultsWe obtained acceptable raw data from 309/330 sEMG measurements in 76/90 infants born at a mean (range) of 30.2 (24.7-34.0) weeks gestation. We found a significant negative association of SampEn with duration of respiratory support (R
conclusionsBaseline SampEn calculated over the first 5 days of life carries prognostic utility for an estimation of subsequent respiratory support and pre-discharge cardiorespiratory stability in preterm infants, both important for planning of treatment and utilization of health care resources.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.