ArticlePediatric research2019
Outcomes of singleton small for gestational age preterm infants exposed to maternal hypertension: a retrospective cohort study.
Article in Pediatric research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed, 20 citations in OpenAlex.
- Perinatal risk factors and 2-year neurodevelopmental outcome of early acute kidney injury in very preterm and very low birth weight infants.Pediatric nephrology (Berlin, Germany) · 2026Article
- Perinatal risk factors for hemodynamically significant patent ductus arteriosus in very low birth weight infants.Clinical and experimental pediatrics · 2026Article
- Clinical characteristics of necrotizing enterocolitis occurring within the first week of life in low-birth-weight preterm infants: a multicenter retrospective study.Frontiers in medicine · 2026Article
- The impact of hypertensive disorders of pregnancy on perinatal outcomes in twin pregnancies: a national multi-center cohort study.BMC pregnancy and childbirth · 2025Article
- Association between hypertensive disorders of pregnancy and disease progression in preterm infants with necrotizing enterocolitis: a retrospective cohort study.European journal of medical research · 2025Article
- Maternal Hypertension Disorders and Neonatal Acute Kidney Injury: Results from the AWAKEN Study.American journal of perinatology · 2024Article
- Association of hypertensive disorder of pregnancy with necrotizing enterocolitis in very preterm infants: A retrospective cohort study.PloS one · 2024Article
- Impact of hypertensive disorders of pregnancy on neonatal outcomes among infants born at 24Frontiers in pediatrics · 2023Article
- Placental morphological features of small for gestational age preterm neonates born to mothers with pregnancy-induced hypertension.Frontiers in pediatrics · 2023Article
- Neonatal outcomes of twins <29 weeks gestation of mothers with hypertensive disorders of pregnancy.Pediatric research · 2022Article
- Mothers with hypertensive disorders of pregnancy increased risk of periventricular leukomalacia in extremely preterm or extremely low birth weight infants: A propensity score analysis.Frontiers in pediatrics · 2022Article
- Neurodevelopmental outcomes of singleton large for gestational age infants <29 weeks' gestation: a retrospective cohort study.Journal of perinatology : official journal of the California Perinatal Association · 2021Article
- Article
- Association between admission hypothermia and outcomes in very low birth weight infants in China: a multicentre prospective study.BMC pediatrics · 2020Observational
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundHypertensive disorders of pregnancy (HDP) are a major cause of small for gestational age (SGA). Preterm SGA infants have higher rates of adverse outcomes than appropriate for gestational age infants. However, the outcomes are not well established in the setting of HDP.
methodsRetrospective population-based study using the Canadian Neonatal Network database from January 1, 2010 to December 31, 2016 of SGA infants <33 weeks gestation. Using multivariable models, we determined the adjusted odds ratios (AORs) with 95% confidence intervals (CI) for mortality, bronchopulmonary dysplasia (BPD), severe intraventricular hemorrhage (IVH), severe retinopathy of prematurity, necrotizing enterocolitis, late-onset sepsis, and patent ductus arteriosus (PDA) in infants of HDP mothers and compared them to infants of non-HDP mothers.
resultsOf the 2081 eligible SGA infants, 1317 (63%) were born to HDP mothers and had lower odds of mortality (AOR 0.57, 95% CI 0.39-0.83) and BPD (AOR 0.69, 95% CI 0.53-0.90). Sub-group analysis demonstrated decreased mortality in 26-28 and 29-32 weeks gestation groups, decreased BPD in 29-32 weeks gestation group, and decreased PDA in <26 weeks gestation group.
conclusionPreterm SGA infants of HDP mothers have lower odds of mortality and BPD compared to infants of non-HDP mothers.
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