Evidence map›Paper›PMID 31086209›Full record

ArticleScientific reports2019

Immune regeneration in irradiated mice is not impaired by the absence of DPP9 enzymatic activity.

Margaret G Gall, Hui Emma Zhang, Quintin Lee, Christopher J Jolly, Geoffrey W McCaughan, Adam Cook, Ben Roediger, Mark D Gorrell

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Margaret G GallCentenary Institute, The University of Sydney Faculty of Medicine and Health, Sydney, New South Wales, Australia.
Hui Emma ZhangCentenary Institute, The University of Sydney Faculty of Medicine and Health, Sydney, New South Wales, Australia.
Quintin LeeCentenary Institute, The University of Sydney Faculty of Medicine and Health, Sydney, New South Wales, Australia.
Christopher J JollyAdult Cancer Program, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW, 2052, Australia.
Geoffrey W McCaughanCentenary Institute, The University of Sydney Faculty of Medicine and Health, Sydney, New South Wales, Australia.
Adam CookCentenary Institute, The University of Sydney Faculty of Medicine and Health, Sydney, New South Wales, Australia.
Ben RoedigerCentenary Institute, The University of Sydney Faculty of Medicine and Health, Sydney, New South Wales, Australia.
Mark D GorrellCentenary Institute, The University of Sydney Faculty of Medicine and Health, Sydney, New South Wales, Australia. m.gorrell@centenary.usyd.edu.au.ORCID http://orcid.org/0000-0002-0528-2604
The University of Sydney · AUUNSW Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ubiquitous intracellular protease dipeptidyl peptidase 9 (DPP9) has roles in antigen presentation and B cell signaling. To investigate the importance of DPP9 in immune regeneration, primary and secondary chimeric mice were created in irradiated recipients using fetal liver cells and adult bone marrow cells, respectively, using wild-type (WT) and DPP9 gene-knockin (DPP9

Indexed as

AnimalsBone Marrow TransplantationCatalytic DomainCell DifferentiationCell ProliferationDipeptidyl-Peptidases and Tripeptidyl-PeptidasesFemaleFetusGene Knock-In TechniquesHematopoietic Stem CellsHematopoietic Stem Cell TransplantationImmune ReconstitutionImmune SystemLiverLoss of Function MutationLymphocytesdipeptidyl peptidase 9, mouseDipeptidyl-Peptidases and Tripeptidyl-Peptidases

Identifiers

PMID31086209
PMCPMC6513830
OpenAlexW2894345294

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.