Evidence map›Paper›PMID 31086091›Full record

ArticleMolecules (Basel, Switzerland)2019

The Role of Astragaloside IV against Cerebral Ischemia/Reperfusion Injury: Suppression of Apoptosis via Promotion of P62-LC3-Autophagy.

Yi Zhang, Ying Zhang, Xiao-Fei Jin, Xiao-Hong Zhou, Xian-Hui Dong, Wen-Tao Yu, Wei-Juan Gao

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
71citing papers in PubMed, 1 pooled it
12.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

71 citing papers in PubMed, 1 synthesis or guideline pooled it, 146 citations in OpenAlex.

  1. Pooled it
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  12. Volatile oil ofFrontiers in pharmacology · 2025
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  14. Comparative analysis ofFrontiers in pharmacology · 2025
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11 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Yi ZhangHebei Key Laboratory of Chinese Medicine Research on Cardio-Cerebrovascular Disease, Hebei University of Chinese Medicine, Shijiazhuang 050200, China. 734910343@163.com.
Ying ZhangHebei Key Laboratory of Chinese Medicine Research on Cardio-Cerebrovascular Disease, Hebei University of Chinese Medicine, Shijiazhuang 050200, China. yingzhang2810@163.com.
Xiao-Fei JinHebei Key Laboratory of Chinese Medicine Research on Cardio-Cerebrovascular Disease, Hebei University of Chinese Medicine, Shijiazhuang 050200, China. jxf1655@163.com.
Xiao-Hong ZhouHebei Key Laboratory of Chinese Medicine Research on Cardio-Cerebrovascular Disease, Hebei University of Chinese Medicine, Shijiazhuang 050200, China. zxh19703@163.com.
Xian-Hui DongHebei Key Laboratory of Chinese Medicine Research on Cardio-Cerebrovascular Disease, Hebei University of Chinese Medicine, Shijiazhuang 050200, China. dongxianhuitj@126.com.
Wen-Tao YuHebei Key Laboratory of Chinese Medicine Research on Cardio-Cerebrovascular Disease, Hebei University of Chinese Medicine, Shijiazhuang 050200, China. ywtawen@163.com.
Wei-Juan GaoHebei Key Laboratory of Chinese Medicine Research on Cardio-Cerebrovascular Disease, Hebei University of Chinese Medicine, Shijiazhuang 050200, China. gwj6088@163.com.
Hebei University of Chinese Medicine · CN

Funding

Hebei Province Graduate Innovative Ability Training Project CXZZBS2018154National Natural Science Foundation of China 81873180
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsApoptosisAutophagybcl-2-Associated X ProteinBrain IschemiaCell LineCell SurvivalMaleMiceProto-Oncogene Proteins c-bcl-2RatsRats, Sprague-DawleyReperfusion InjurySaponinsTriterpenesastragaloside Abcl-2-Associated X ProteinBCL2 protein, humanProto-Oncogene Proteins c-bcl-2SaponinsTriterpenesapoptosisAstragaloside IVautophagycerebral ischemia/reperfusion injurymechanism

Identifiers

PMID31086091
PMCPMC6539971
OpenAlexW2944262472

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.