Evidence map›Paper›PMID 31086077›Full record

ReviewMolecules (Basel, Switzerland)2019

Terrestrial Microorganisms: Cell Factories of Bioactive Molecules with Skin Protecting Applications.

Laure-Anne Peyrat, Nikolaos Tsafantakis, Katerina Georgousaki, Jamal Ouazzani, Olga Genilloud, Ioannis P Trougakos, Nikolas Fokialakis

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
6.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
  2. Spent Brewer's Yeast Lysis Enables aInternational journal of molecular sciences · 2024
    Review
  3. Article
  4. Effects ofJournal of microbiology and biotechnology · 2021
    Article
  5. Review
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Laure-Anne PeyratDepartment of Pharmacognosy and Natural Products Chemistry, Faculty of Pharmacy, National and Kapodistrian University of Athens, 15771 Athens, Greece. laure_anne.peyrat@yahoo.fr.
Nikolaos TsafantakisDepartment of Pharmacognosy and Natural Products Chemistry, Faculty of Pharmacy, National and Kapodistrian University of Athens, 15771 Athens, Greece. ntsafantakis@pharm.uoa.gr.
Katerina GeorgousakiDepartment of Pharmacognosy and Natural Products Chemistry, Faculty of Pharmacy, National and Kapodistrian University of Athens, 15771 Athens, Greece. kat_georgousaki@hotmail.com.
Jamal OuazzaniInstitut de Chimie des Substances Naturelles (ICSN), Centre National de la Recherche Scientifique, 91198 Gif-sur-Yvette, France. Jamal.Ouazzani@cnrs.fr.
Olga GenilloudFundación MEDINA, 18016 Granada, Spain. olga.genilloud@medinaandalucia.es.
Ioannis P TrougakosDepartment of Cell Biology and Biophysics, Faculty of Biology, National and Kapodistrian University of Athens, 15784 Athens, Greece. itrougakos@biol.uoa.gr.
Nikolas FokialakisDepartment of Pharmacognosy and Natural Products Chemistry, Faculty of Pharmacy, National and Kapodistrian University of Athens, 15771 Athens, Greece. fokialakis@pharm.uoa.gr.
National and Kapodistrian University of Athens · GRFundación Medina · ESInstitut de Chimie des Substances Naturelles · FR

Funding

FP7 People: Marie-Curie Actions No. 612276
6 · The paper itself

Abstract

It is well known that terrestrial environments host an immense microbial biodiversity. Exposed to different types of stress, such as UV radiation, temperature fluctuations, water availability and the inter- / intra-specific competition for resources, terrestrial microorganisms have been evolved to produce a large spectrum of bioactive molecules. Bacteria, archaea, protists, fungi and algae have shown a high potential of producing biomolecules for pharmaceutical or other industrial purposes as they combine a sustainable, relatively low-cost and fast-production process. Herein, we provide an overview of the different bioactive molecules produced by terrestrial microorganisms with skin protecting applications. The high content in polyphenolic and carotenoid compounds produced by several strains, as well as the presence of exopolysaccharides, melanins, indole and pyrrole derivatives, mycosporines, carboxylic acids and other molecules, are discussed in the context of their antioxidant, photo-protective and skin-whitening activity. Relevant biotechnological tools developed for the enhanced production of high added value natural products, as well as the protecting effect of some antioxidant, hydrolytic and degrading enzymes are also discussed. Furthermore, we describe classes of microbial compounds that are used or have the potential to be used as antimicrobials, moisturizers, biosurfactants, pigments, flavorings and fragrances.

Indexed as

AntioxidantsArchaeaBacteriaBiological ProductsBiotechnologyCosmeticsFungiAntioxidantsBiological ProductsCosmeticsantioxidantcosmeticsphoto-protectiveskin-whiteningterrestrial microorganisms

Identifiers

PMID31086077
PMCPMC6539289
OpenAlexW2944214449

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.