Evidence map›Paper›PMID 31086026›Full record

ArticleMarine drugs2019

Flaccidoxide-13-Acetate-Induced Apoptosis in Human Bladder Cancer Cells is through Activation of p38/JNK, Mitochondrial Dysfunction, and Endoplasmic Reticulum Stress Regulated Pathway.

Yu-Jen Wu, Tzu-Rong Su, Guo-Fong Dai, Jui-Hsin Su, Chih-I Liu

Abstract read
In one paragraph

Article in Marine drugs, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
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  6. Review
  7. Stellettin B Isolated fromInternational journal of cell biology · 2022
    Article
  8. Article
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  10. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yu-Jen WuDepartment of Nursing, Meiho University, Pingtung 91202, Taiwan. x00002180@meiho.edu.tw.
Tzu-Rong SuAntai Medical Care Cooperation Antai Tian-Sheng Memorial Hospital, Pingtung 92842, Taiwan. a081002@mail.tsmh.org.tw.
Guo-Fong DaiDepartment of Biological Technology, Meiho University, Pingtung 91202, Taiwan. fwind101@gmail.com.
Jui-Hsin SuNational Museum of Marine Biology and Aquarium, Pingtung 94450, Taiwan. x2219@nmmba.gov.tw.
Chih-I LiuDepartment of Nursing, Meiho University, Pingtung 91202, Taiwan. x00002177@meiho.edu.tw.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Flaccidoxide-13-acetate, an active compound isolated from cultured-type soft coral

Indexed as

AnimalsApoptosisCaspase 3Caspase 9Cell Line, TumorCell MovementDiterpenesEndoplasmic Reticulum StressHumansMAP Kinase Signaling SystemMembrane Potential, MitochondrialMitochondriaPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktProto-Oncogene Proteins c-bcl-2RabbitsBCL2 protein, humanCASP3 protein, humanCASP9 protein, humanCaspase 3Caspase 9Diterpenesflaccidoxide-13-acetatePhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktProto-Oncogene Proteins c-bcl-2Transcription Factor CHOPapoptosiscultured soft coral Sinularia gibberosaflaccidoxide-13-acetatehuman bladder cancermitochondrial dysfunctionp38/JNKPERK-eIF2α-ATF6-CHOP pathway

Identifiers

PMID31086026
PMCPMC6562797

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.