Evidence map›Paper›PMID 31085998›Full record

ArticleInternational journal of molecular sciences2019

A Natural mtDNA Polymorphism in Complex III Is a Modifier of Healthspan in Mice.

Misa Hirose, Axel Künstner, Paul Schilf, Anna Katharina Tietjen, Olaf Jöhren, Patricia Huebbe, Gerald Rimbach, Jan Rupp, Markus Schwaninger, Hauke Busch and 1 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. mtTB: A Web-Based R/Shiny App for Pulmonary Tuberculosis Screening.Frontiers in cellular and infection microbiology · 2022
    Article
  5. Article
  6. Review
  7. Article
  8. mtDNA and Mitochondrial Stress Signaling in Human Diseases: A Special Issue.International journal of molecular sciences · 2020
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Misa HiroseLuebeck Institute of Experimental Dermatology, University of Luebeck, 23562 Luebeck, Germany. Misa.Hirose@uksh.de.
Axel KünstnerLuebeck Institute of Experimental Dermatology and Institute for Cardiogenetics, University of Luebeck, 23562 Luebeck, Germany. axel.kuenstner@uni-luebeck.de.ORCID 0000-0003-0692-2105
Paul SchilfLuebeck Institute of Experimental Dermatology, University of Luebeck, 23562 Luebeck, Germany. Paul.Schilf@uksh.de.
Anna Katharina TietjenLuebeck Institute of Experimental Dermatology, University of Luebeck, 23562 Luebeck, Germany. annakatharinatietjen@gmail.com.
Olaf JöhrenCenter of Brain, Behavior & Metabolism, University of Luebeck, 23562 Luebeck, Germany. olaf.joehren@uni-luebeck.de.
Patricia HuebbeInstitute of Human Nutrition and Food Science, University of Kiel, 24098 Kiel, Germany. huebbe@foodsci.uni-kiel.de.
Gerald RimbachInstitute of Human Nutrition and Food Science, University of Kiel, 24098 Kiel, Germany. rimbach@foodsci.uni-kiel.de.
Jan RuppDepartment of Infectious Disease and Microbiology, University of Luebeck, 23562 Luebeck, Germany. Jan.Rupp@uksh.de.
Markus SchwaningerInstitute of Experimental and Clinical Pharmacology and Toxicology, University of Luebeck, 23562 Luebeck, Germany. markus.schwaninger@pharma.uni-luebeck.de.
Hauke BuschLuebeck Institute of Experimental Dermatology, Institute for Cardiogenetics and Center for research of inflammatory skin disease (CRIS), University of Luebeck, 23562 Luebeck, Germany. hauke.busch@uni-luebeck.de.ORCID 0000-0003-4763-4521
Saleh M IbrahimLuebeck Institute of Experimental Dermatology and Center for research of inflammatory skin disease (CRIS), University of Luebeck, 23562 Luebeck, Germany. Saleh.Ibrahim@uksh.de.
University of Lübeck · DEInstitute for Integrative and Experimental Genomics · DE

Funding

Bundesministerium für Bildung, Wissenschaft, Forschung und Technologie 0315892BDeutsche Forschungsgemeinschaft EXC 22167-390884018Deutsche Forschungsgemeinschaft EXC306/2TANITA Healthy Weight Community Trust 2014
6 · The paper itself

Abstract

In this study, we provide experimental evidence that a maternally inherited polymorphism in the mitochondrial cytochrome b gene (

Indexed as

AnimalsBacteroidetesDNA, MitochondrialFemaleGenes, MitochondrialMaleMiceMice, Inbred C57BLMitochondrial MembranesMutationOxidative StressPolymorphism, Single NucleotideReactive Oxygen SpeciesDNA, MitochondrialReactive Oxygen Speciesage-related diseasescomplex IIIconplastic mouse strainsgut microbiotahealthspanmiddle-aged obesitymitochondrial DNA polymorphismsmitochondrially encoded cytochrome b genemt-Cytb

Identifiers

PMID31085998
PMCPMC6539666
OpenAlexW2944637162

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.