Evidence map›Paper›PMID 31085796›Full record

ArticleAging2019

RON and RONΔ160 promote gastric cancer cell proliferation, migration, and adaption to hypoxia via interaction with β-catenin.

Donghui Zhou, Ling Huang, Yong Zhou, Tao Wei, Lina Yang, Chao Li

Open access · greenAbstract read
In one paragraph

Article in Aging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Hypoxia-induced alternative splicing: the 11th Hallmark of Cancer.Journal of experimental & clinical cancer research : CR · 2020
    Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Donghui ZhouDepartment of Oncology, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310003, China.
Ling HuangDepartment of Oncology, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310003, China.
Yong ZhouDepartment of Oncology, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310003, China.
Tao WeiDepartment of Oncology, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310003, China.
Lina YangDepartment of Oncology, the Affiliated Dongnan Hospital of Xiamen University, Zhangzhou, Fujian 363000, China.
Chao LiDepartment of Medical Oncology, Affiliated Hospital of Inner Mongolia Medical University, Huhhot, Inner Mongolia 010030, China.
First Affiliated Hospital Zhejiang University · CNInner Mongolia Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aberrant accumulation of the receptor tyrosine kinase recepteur d'origine nantais (RON) has been verified in gastric adenocarcinoma. Upregulation of RON and its splice variant RONΔ160 contribute to the growth and migration in gastric cancer cells

Indexed as

Adaptation, PhysiologicalAnimalsbeta CateninCell Line, TumorCell MovementCell ProliferationFemaleGene Expression Regulation, NeoplasticHypoxia-Inducible Factor 1, alpha SubunitMiceMice, NudeMutationNeoplasms, ExperimentalOxygenProtein BindingRandom Allocationbeta CateninCTNNB1 protein, humanHIF1A protein, humanHypoxia-Inducible Factor 1, alpha SubunitOxygenReceptor Protein-Tyrosine KinasesRON proteinaginggastric cancerhypoxiarecepteur d’origine nantaisRONΔ160senescenceβ-catenin

Identifiers

PMID31085796
PMCPMC6535062
OpenAlexW2945824521

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.