Evidence map›Paper›PMID 31085684›Full record

ArticleMolecular and cellular biology2019

Bugs as Cancer Drugs: Challenges and Opportunities.

Phillip J Daschner, Avraham Rasooly, Jeffrey D White

Abstract read
In one paragraph

Article in Molecular and cellular biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Phillip J DaschnerNational Cancer Institute Division of Cancer Biology, Rockville, Maryland, USA.
Avraham RasoolyNational Cancer Institute, Division of Cancer Treatment and Diagnosis, Rockville, Maryland, USA rasoolya@mail.nih.gov.
Jeffrey D WhiteNational Cancer Institute, Division of Cancer Treatment and Diagnosis, Rockville, Maryland, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The first nonsurgical cancer therapy was bacterial therapy introduced in 1891 to treat solid tumors. Because in many cases it was harmful and ineffective, and with the emergence of radiotherapy and chemotherapy, bacterial therapy was discontinued. Motivated by the need to improve targeting of solid tumors and in light of recent progress made in developing microbial therapies, the National Cancer Institute has for the first time issued funding opportunities to stimulate research on bacterium-based cancer therapies for conditions under which current cancer therapies are inadequate.

Indexed as

BacteriaBacterial Physiological PhenomenaBacterial ProteinsBiological TherapyHumansNational Cancer Institute (U.S.)NeoplasmsTranslational Research, BiomedicalUnited StatesBacterial Proteinscancermicrobialtherapy

Identifiers

PMID31085684
PMCPMC6639246

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.