Evidence map›Paper›PMID 31085637›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2019

Microbial production of methyl anthranilate, a grape flavor compound.

Zi Wei Luo, Jae Sung Cho, Sang Yup Lee

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 115 citations in OpenAlex.

  1. Biosynthesis of vanillin glucoside inSynthetic and systems biotechnology · 2027
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  6. Metabolic engineering ofProceedings of the National Academy of Sciences of the United States of America · 2024
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  7. Article
  8. Article
  9. Article
  10. Article
  11. Styrene Production in Genetically EngineeredBiotech (Basel (Switzerland)) · 2024
    Article
  12. Article
  13. Review
  14. Article
  15. EngineeredFrontiers in microbiology · 2023
    Article
  16. Article
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Zi Wei LuoMetabolic and Biomolecular Engineering National Research Laboratory, Department of Chemical and Biomolecular Engineering (BK21 Plus Program), Institute for the BioCentury, Korea Advanced Institute of Science and Technology, 34141 Daejeon, Republic of Korea.ORCID 0000-0001-6018-9368
Jae Sung ChoMetabolic and Biomolecular Engineering National Research Laboratory, Department of Chemical and Biomolecular Engineering (BK21 Plus Program), Institute for the BioCentury, Korea Advanced Institute of Science and Technology, 34141 Daejeon, Republic of Korea.ORCID 0000-0002-5237-4907
Sang Yup LeeMetabolic and Biomolecular Engineering National Research Laboratory, Department of Chemical and Biomolecular Engineering (BK21 Plus Program), Institute for the BioCentury, Korea Advanced Institute of Science and Technology, 34141 Daejeon, Republic of Korea; leesy@kaist.ac.kr.ORCID 0000-0003-0599-3091
Korea Advanced Institute of Science and Technology · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Methyl anthranilate (MANT) is a widely used compound to give grape scent and flavor, but is currently produced by petroleum-based processes. Here, we report the direct fermentative production of MANT from glucose by metabolically engineered

Indexed as

Corynebacterium glutamicumEscherichia coliBacterial ProteinsBioreactorsFermentationFlavoring AgentsMetabolic EngineeringMetabolic Networks and PathwaysMethyltransferasesortho-AminobenzoatesPlant ProteinsRecombinant ProteinsBacterial ProteinsFlavoring Agentsmethyl anthranilateMethyltransferasesortho-AminobenzoatesPlant ProteinsRecombinant ProteinsCorynebacterium glutamicumEscherichia colimetabolic engineeringmethyl anthranilatetwo-phase fermentation

Identifiers

PMID31085637
PMCPMC6561195
OpenAlexW2946351703

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.