Evidence map›Paper›PMID 31085547›Full record

ArticleBiology open2019

Xenotransplantation of Human glioblastoma in Zebrafish larvae:

Luis A Vargas-Patron, Nathalie Agudelo-Dueñas, Jorge Madrid-Wolff, Juan A Venegas, John M González, Manu Forero-Shelton, Veronica Akle

Open access · goldAbstract read
In one paragraph

Article in Biology open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 2 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 29 citations in OpenAlex.

  1. Glioblastoma research on zebrafish xenograft models: a systematic review.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2024
    Pooled it
  2. Pooled it
  3. Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Review
  11. Zebrafish Models of Paediatric Brain Tumours.International journal of molecular sciences · 2022
    Review
  12. Article
  13. Article
  14. Modeling Brain Tumors: A Perspective Overview ofFrontiers in molecular neuroscience · 2022
    Review
  15. Article
  16. Article
  17. Zebrafish as a Model for Anticancer Nanomedicine Studies.Pharmaceuticals (Basel, Switzerland) · 2021
    Review
  18. Article
  19. Review
  20. Tipping the Scales With Zebrafish to Understand Adaptive Tumor Immunity.Frontiers in cell and developmental biology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Luis A Vargas-PatronLaboratory of Neurosciences and Circadian Rhythms, School of Medicine, Universidad de los Andes, Bogota, 111711, Colombia.
Nathalie Agudelo-DueñasLaboratory of Neurosciences and Circadian Rhythms, School of Medicine, Universidad de los Andes, Bogota, 111711, Colombia.ORCID http://orcid.org/0000-0003-0983-0492
Jorge Madrid-WolffBiophysics Group, Department of Physics, Universidad de los Andes, Bogota, 111711, Colombia.ORCID http://orcid.org/0000-0003-3945-538X
Juan A VenegasBiomedical Sciences Laboratory, School of Medicine, Universidad de los Andes, Bogota, 111711, Colombia.
John M GonzálezBiomedical Sciences Laboratory, School of Medicine, Universidad de los Andes, Bogota, 111711, Colombia.ORCID http://orcid.org/0000-0001-6925-0620
Manu Forero-SheltonBiophysics Group, Department of Physics, Universidad de los Andes, Bogota, 111711, Colombia.ORCID http://orcid.org/0000-0002-7989-0311
Veronica AkleLaboratory of Neurosciences and Circadian Rhythms, School of Medicine, Universidad de los Andes, Bogota, 111711, Colombia v.akle@uniandes.edu.co.ORCID http://orcid.org/0000-0002-2050-5511
Universidad de Los Andes · CO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glioblastoma (GBM) is the most prevalent type of primary brain tumor. Treatment options include maximal surgical resection and drug-radiotherapy combination. However, patient prognosis remains very poor, prompting the search for new models for drug discovery and testing, especially those that allow assessment of

Indexed as

Flow cytometryGlioblastomaMicroscopyXenograftZebrafish

Identifiers

PMID31085547
PMCPMC6550087
OpenAlexW2945706155

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.