Evidence map›Paper›PMID 31085512›Full record

ArticleAntimicrobial agents and chemotherapy2019

Using Mycobacterium tuberculosis Single-Nucleotide Polymorphisms To Predict Fluoroquinolone Treatment Response.

Marva Seifert, Edmund Capparelli, Donald G Catanzaro, Timothy C Rodwell

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. A Rare D94F Change inAntimicrobial agents and chemotherapy · 2019
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Marva SeifertDepartment of Medicine, University of California San Diego, La Jolla, California, USA mseifert@ucsd.edu trodwell@ucsd.edu.ORCID 0000-0002-7554-6396
Edmund CapparelliDepartment of Pediatrics, University of California San Diego, La Jolla, California, USA.
Donald G CatanzaroDepartment of Biological Sciences, University of Arkansas, Fayetteville, Arkansas, USA.ORCID 0000-0003-1760-0574
Timothy C RodwellDepartment of Medicine, University of California San Diego, La Jolla, California, USA mseifert@ucsd.edu trodwell@ucsd.edu.
University of California San Diego · USUniversity of Arkansas at Fayetteville · US

Funding

UC San Diego Clinical and Translational Research InstituteUL1TR001442 · NCATS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FIRESTEIN, GARY S, HOGARTH, MICHAEL · 2015 to 2024
$88.3M
VirologyP30AI036214 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Maile Ann Young Karris · 1994 to 2026
$78.4M
An Integrated Tabletop Platform for Rapid Detection of XDR-TB in Clinical SamplesR01AI111435 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI RODWELL, TIMOTHY CHARLES · 2014 to 2018
$5.4M
Training in the Next Generation in Respiratory ScienceT32HL134632 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MALHOTRA, ATUL, POWELL, FRANK L. · 2017 to 2021
$2.1M
Culture-free next generation sequencing for rapid detection of drug-resistant tuberculosisR21AI135756 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI RODWELL, TIMOTHY CHARLES · 2018 to 2019
$500k
NCATS NIH HHS UL1 TR001442NHLBI NIH HHS T32 HL134632NIAID NIH HHS P30 AI036214NIAID NIH HHS R01 AI111435NIAID NIH HHS R21 AI135756
6 · The paper itself

Abstract

Clinical phenotypic fluoroquinolone susceptibility testing of

Indexed as

Antitubercular AgentsFluoroquinolonesGatifloxacinLevofloxacinMicrobial Sensitivity TestsMoxifloxacinMycobacterium tuberculosisOfloxacinPolymorphism, Single NucleotideAntitubercular AgentsFluoroquinolonesGatifloxacinLevofloxacinMoxifloxacinOfloxacinfluoroquinolonepharmacodynamicspharmacokineticstreatmenttuberculosis

Identifiers

PMID31085512
PMCPMC6591594
OpenAlexW2944772945

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.