Evidence map›Paper›PMID 31085511›Full record

ArticleAntimicrobial agents and chemotherapy2019

Efficient Inactivation of Clinically Relevant Antimicrobial Drug Concentrations by BacT/Alert or Bactec Resin-Containing Media in Simulated Adult Blood Cultures.

Giulia Menchinelli, Flora Marzia Liotti, Liliana Giordano, Giulia De Angelis, Maurizio Sanguinetti, Teresa Spanu, Brunella Posteraro

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.7field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Giulia MenchinelliIstituto di Microbiologia, Università Cattolica del Sacro Cuore, Rome, Italy.
Flora Marzia LiottiIstituto di Microbiologia, Università Cattolica del Sacro Cuore, Rome, Italy.
Liliana GiordanoIstituto di Microbiologia, Università Cattolica del Sacro Cuore, Rome, Italy.
Giulia De AngelisIstituto di Microbiologia, Università Cattolica del Sacro Cuore, Rome, Italy.
Maurizio SanguinettiIstituto di Microbiologia, Università Cattolica del Sacro Cuore, Rome, Italy maurizio.sanguinetti@unicatt.it.ORCID 0000-0002-9780-7059
Teresa Spanu *Istituto di Microbiologia, Università Cattolica del Sacro Cuore, Rome, Italy.
Brunella Posteraro *Istituto di Patologia e Semeiotica Medica, Università Cattolica del Sacro Cuore Rome, Rome, Italy.
Università Cattolica del Sacro Cuore · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We assessed the antimicrobial-inactivation capability of BacT/Alert (FA Plus and FN Plus) or Bactec (Plus Aerobic/F and Plus Anaerobic/F) media for 40 antibiotic-bacterium combinations in simulated adult blood cultures. Aside from high recovery rates (93.2% and 88.4%, respectively), we showed that at the lowest but clinically relevant antibiotic concentrations, both BacT/Alert and Bactec media recovered all the organisms tested with drugs except for

Indexed as

AdultAnti-Bacterial AgentsBacteremiaBacteriaBlood CultureCulture MediaEscherichia coliHumansMeropenemPseudomonas aeruginosaTime FactorsAnti-Bacterial AgentsCulture MediaMeropenemblood culture systemdrug inactivationpersonalized therapy

Identifiers

PMID31085511
PMCPMC6591622
OpenAlexW2944807135

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.