Evidence map›Paper›PMID 31085121›Full record

ArticleCytotherapy2019

Feasibility and cost analysis of day 4 granulocyte colony-stimulating factor mobilized peripheral blood progenitor cell collection from HLA-matched sibling donors.

Laura F Newell, Kelsea M Shoop, Rebekah J Knight, Sara N Murray, Rogelyn P Kwock, Carol E Jacoby, Susan Slater, Bryon E Allen, Casondra Ottowa, Brad Cota and 4 more

Open access · greenAbstract read
In one paragraph

Article in Cytotherapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Single Apheresis Session on the 4th Day of Granulocyte Colony-Stimulating Factor Administration Seems Convenient to Collect Enough Peripheral Blood Stem Cells from Healthy Donors.Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2024
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Laura F NewellKnight Cancer Institute, Hematology and Medical Oncology, Oregon Health & Science University, Portland, Oregon, USA. Electronic address: newelll@ohsu.edu.
Kelsea M ShoopHematopoietic Cell Processing Laboratory, Hospital and Clinics, Oregon Health & Science University, Portland Oregon, USA.
Rebekah J KnightHematopoietic Cell Processing Laboratory, Hospital and Clinics, Oregon Health & Science University, Portland Oregon, USA.
Sara N MurrayHematopoietic Cell Processing Laboratory, Hospital and Clinics, Oregon Health & Science University, Portland Oregon, USA.
Rogelyn P KwockKnight Cancer Institute, Hematology and Medical Oncology, Oregon Health & Science University, Portland, Oregon, USA.
Carol E JacobyKnight Cancer Institute, Hematology and Medical Oncology, Oregon Health & Science University, Portland, Oregon, USA.
Susan SlaterKnight Cancer Institute, Hematology and Medical Oncology, Oregon Health & Science University, Portland, Oregon, USA.
Bryon E AllenKnight Cancer Institute, Hematology and Medical Oncology, Oregon Health & Science University, Portland, Oregon, USA.
Casondra OttowaApheresis Unit, Hospital and Clinics, Oregon Health & Science University, Portland Oregon, USA.
Brad CotaHospital and Clinics Financial Services, Oregon Health & Science University, Portland Oregon, USA.
Peggy L AppelNorthwest Marrow Transplant Program, Oregon Health & Science University, Portland Oregon, USA.
Rachel J CookKnight Cancer Institute, Hematology and Medical Oncology, Oregon Health & Science University, Portland, Oregon, USA.
Richard T MaziarzKnight Cancer Institute, Hematology and Medical Oncology, Oregon Health & Science University, Portland, Oregon, USA.
Gabrielle MeyersKnight Cancer Institute, Hematology and Medical Oncology, Oregon Health & Science University, Portland, Oregon, USA.
Oregon Health & Science University · USOregon Health and Science University Hospital · US

Funding

Infectious Events in Pregnancy: PlGF Contributes to Maternal MorbidityK23HD091369 · NICHD · OREGON HEALTH & SCIENCE UNIVERSITY · PI NEWELL, LAURA F · 2017 to 2020
$634k
NICHD NIH HHS K23 HD091369
6 · The paper itself

Abstract

backgroundGuidelines recommend treatment with 4-5 days of granulocyte colony-stimulating factor (G-CSF) for optimal donor peripheral blood progenitor cell (PBPC) mobilization followed by day 5 collection. Given that some autologous transplant recipients achieve adequate collection by day 4 and the possibility that some allogeneic donors may maximally mobilize PBPC before day 5, a feasibility study was performed evaluating day 4 allogeneic PBPC collection.

methodsHLA-matched sibling donors underwent collection on day 4 of G-CSF for peripheral blood (PB) CD34

resultsOf the 101 patient/donor pairs, 50 (49.5%) had adequate PBPC collection on day 4, with a median PB CD34 DISCUSSION: Day 4 PB CD34

Indexed as

AdolescentAdultAgedAntigens, CD34Blood Cell CountCosts and Cost AnalysisFeasibility StudiesFemaleGraft vs Host DiseaseGranulocyte Colony-Stimulating FactorHematopoietic Stem Cell MobilizationHematopoietic Stem Cell TransplantationHumansMaleMiddle AgedSiblingsAntigens, CD34Granulocyte Colony-Stimulating Factorhematopoietic progenitor cellshematopoietic stem cell transplantationperipheral blood stem cellsstem cell mobilization

Identifiers

PMID31085121
PMCPMC7219570
OpenAlexW2914745139

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.