ArticleInternational journal of hygiene and environmental health2019
A biomonitoring assessment of secondhand exposures to electronic cigarette emissions.
Article in International journal of hygiene and environmental health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 25 citations in OpenAlex.
- Secondhand electronic cigarette aerosol in vehicles impacts indoor air quality.Drug and alcohol dependence · 2023Article
- Influence of puff topographies on e-liquid heating temperature, emission characteristics and modeled lung deposition of Puff BarAerosol science and technology : the journal of the American Association for Aerosol Research · 2023Article
- Effects of electronic cigarettes and hookah (waterpipe) use on home air quality.Tobacco control · 2023Article
- Computational modeling method to estimate secondhand exposure potential from exhalations during e-vapor product use under various real-world scenarios.Internal and emergency medicine · 2022Article
- Geometric Mean Serum Cotinine Concentrations Confirm a Continued Decline in Secondhand Smoke Exposure among U.S. Nonsmokers-NHANES 2003 to 2018.International journal of environmental research and public health · 2022Article
- Influence of E-Liquid Humectants, Nicotine, and Flavorings on Aerosol Particle Size Distribution and Implications for Modeling Respiratory Deposition.Frontiers in public health · 2022Article
- Tracing the movement of electronic cigarette flavor chemicals and nicotine from refill fluids to aerosol, lungs, exhale, and the environment.Chemosphere · 2022Article
- Toxicology of flavoring- and cannabis-containing e-liquids used in electronic delivery systems.Pharmacology & therapeutics · 2021Review
- Firsthand and Secondhand Exposure Levels of Maltol-Flavored Electronic Nicotine Delivery System Vapors Disrupt Amino Acid Metabolism.Toxicological sciences : an official journal of the Society of Toxicology · 2021Article
- Use of E-Cigarettes and Associated Factors among Youth in Thailand.Asian Pacific journal of cancer prevention : APJCP · 2021Article
- Recent updates on biomarkers of exposure and systemic toxicity in e-cigarette users and EVALI.American journal of physiology. Lung cellular and molecular physiology · 2021Review
- Room air constituent concentrations from use of electronic nicotine delivery systems and cigarettes using different ventilation conditions.Scientific reports · 2021Article
- The Effects of Nicotine on Development.Pediatrics · 2020Review
- A custom-built low-cost chamber for exposing rodents to e-cigarette aerosol: practical considerations.Inhalation toxicologyArticle
Corrections and comments
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Authors and funding
11 authors at 4 institutions in 1 country.
Funding
Abstract
backgroundElectronic cigarette (e-cigarette) conventions regularly bring together thousands of users around the world. In these environments, secondhand exposures to high concentrations of e-cigarette emissions are prevalent. Some biomarkers for tobacco smoke exposure may be used to characterize secondhand e-cigarette exposures in such an environment.
methodsParticipants who did not use any tobacco product attended four separate e-cigarette events for approximately six hours. Urine and saliva samples were collected from participants prior to the event, immediately after the event, 4-h after the event, and the next morning (first void). Urine samples from 34 participants were analyzed for cotinine, trans-3'-hydroxycotinine, S-(3-hydroxypropyl)-N-acetylcysteine (3-HPMA), S-carboxyethyl-N-acetylcysteine (CEMA), select tobacco-specific nitrosamines (TSNAs), and 8-isoprostane. Saliva samples were analyzed for cotinine and trans-3'-hydroxycotinine.
resultsData from 28 of 34 participants were used in the data analysis. Creatinine-adjusted urinary cotinine concentrations increased up to 13-fold and peaked 4-h after completed exposure (range of adjusted geometric means [AGMs] = 0.352-2.31 μg/g creatinine). Salivary cotinine concentrations were also the highest 4-h after completed exposure (range of AGMs = 0.0373-0.167 ng/mL). Salivary cotinine and creatinine-corrected concentrations of urinary cotinine, trans-3'-hydroxycotinine, CEMA, and 3-HPMA varied significantly across sampling times. Urinary and salivary cotinine, urinary trans-3'-hydroxycotinine, and urinary 3-HPMA concentrations also varied significantly across events.
conclusionSecondhand e-cigarette exposures lasting six hours resulted in significant changes in exposure biomarker concentrations of both nicotine and acrolein but did not change exposure to tobacco-specific nitrosamines. Additional research is needed to understand the relationship between biomarker concentrations and environmental concentrations of toxicants in e-cigarette emissions.
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