Evidence map›Paper›PMID 31084917›Full record

ArticleThe Journal of pediatrics2019

Does Tonsillectomy Increase Obesity Risk in Children with Down Syndrome?

Amanda G Ruiz, Dexiang Gao, David G Ingram, Francis Hickey, Matthew A Haemer, Norman R Friedman

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of pediatrics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Craniofacial Surgery in Children With Down Syndrome: A 6-decade Scoping Review.Plastic and reconstructive surgery. Global open · 2025
    Article
  2. Weight Gain in Obese Children After Intracapsular Tonsillectomy.Laryngoscope investigative otolaryngology · 2025
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Amanda G RuizDepartment of Otolaryngology, University of Colorado School of Medicine and Children's Hospital-Colorado, Aurora, CO.
Dexiang GaoDepartment of Pediatrics, University of Colorado School of Medicine, Aurora, CO.
David G IngramDepartment of Pediatrics, Division of Pulmonary and Sleep Medicine, University of Missouri-Kansas City School of Medicine and Children's Mercy Hospital, Kansas City, MO.
Francis HickeySie Center for Down syndrome, Children's Hospital Colorado, Aurora, CO.
Matthew A HaemerDepartment of Pediatrics, University of Colorado School of Medicine, Aurora, CO; Lifestyle Medicine Weight Management Program, Children's Hospital Colorado, Aurora, CO.
Norman R FriedmanDepartment of Otolaryngology, University of Colorado School of Medicine and Children's Hospital-Colorado, Aurora, CO. Electronic address: Norman.Friedman@childrenscolorado.org.
University of Colorado Denver · USChildren's Hospital Colorado · USChildren's Mercy Hospital · US

Funding

CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR025780 · NCRR · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2008 to 2011
$61.3M
Tailoring of Childhood Obesity Screening and Counseling for Latino Families with Preschool-Aged ChildrenK23DK104090 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI HAEMER, MATTHEW A. · 2016 to 2020
$949k
NCRR NIH HHS UL1 RR025780NIDDK NIH HHS K23 DK104090
6 · The paper itself

Abstract

objectivesTo examine weight changes relative to surgical success in children with Down syndrome and obstructive sleep apnea (OSA). STUDY

designRetrospective chart review of children with Down syndrome undergoing tonsillectomy from 2005 to 2016 for OSA at a tertiary care children's hospital. Only patients with pre-and postoperative polysomnogram within 6 months of tonsillectomy were included. Demographics, weight, height, and polysomnogram data were collected. Body mass index (BMI), expressed as a percentage of the 95th percentile (%BMI

resultsA total of 78 patients with Down syndrome whose mean age was 5.29 years at time of tonsillectomy were identified. There was no difference between best-fit curves of %BMI

conclusionsTonsillectomy neither alters the BMI trajectory of children with Down syndrome, nor changes differentially the risk for obesity in children whose OSA did or did not resolve after surgery.

Indexed as

Body Mass IndexTonsillectomyAdolescentChildChild, PreschoolDown SyndromeFemaleHumansInfantMalePediatric ObesityRegression AnalysisRetrospective StudiesSleep Apnea, ObstructiveBMIobstructive sleep apneapolysomnogramweight gain

Identifiers

PMID31084917
PMCPMC7004651
OpenAlexW2944637895

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.