Evidence map›Paper›PMID 31084706›Full record

ArticleeLife2019

A multiplexed DNA FISH strategy for assessing genome architecture in

Brandon D Fields, Son C Nguyen, Guy Nir, Scott Kennedy

Open access · goldAbstract read
In one paragraph

Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 57 citations in OpenAlex.

  1. Programmed DNA elimination was present in the last common ancestor ofbioRxiv : the preprint server for biology · 2026
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  16. The 3D Genome: From Structure to Function.International journal of molecular sciences · 2021
    Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Brandon D Fields *Laboratory of Genetics, University of Wisconsin-Madison, Madison, United States.ORCID 0000-0002-8410-9374
Son C Nguyen *Department of Genetics, Harvard Medical School, Boston, United States.
Guy NirDepartment of Genetics, Harvard Medical School, Boston, United States.ORCID 0000-0001-9268-6596
Scott KennedyDepartment of Genetics, Harvard Medical School, Boston, United States.ORCID 0000-0002-7974-8155
Harvard University · USUniversity of Wisconsin–Madison · US

Funding

Culling the human genome of disease variants using ultraconserved elementsR01HD091797 · NICHD · HARVARD MEDICAL SCHOOL · PI WU, CHAO-TING · 2016 to 2020
$5.5M
Small Regulatory RNA Functions In The NucleusR01GM088289 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI KENNEDY, SCOTT G · 2009 to 2022
$4.4M
The inheritance of position: It's not just who you are, it's where you areDP1GM106412 · NIGMS · HARVARD MEDICAL SCHOOL · PI WU, CHAO-TING · 2012 to 2016
$4.2M
Technologies for visualizing the genome in situR01GM123289 · NIGMS · HARVARD MEDICAL SCHOOL · PI WU, CHAO-TING · 2017 to 2020
$2.5M
NICHD NIH HHS R01 HD091797NIGMS NIH HHS DP1 GM106412NIGMS NIH HHS R01 GM088289NIGMS NIH HHS R01 GM123289NIH HHS 5DP1GM106412NIH HHS R01GM123289NIH HHS R01HD091797NIH HHS RO1GM088289
6 · The paper itself

Abstract

Eukaryotic DNA is highly organized within nuclei and this organization is important for genome function. Fluorescent

Indexed as

Genetic VariationGenome, HelminthAnimalsCaenorhabditis elegansDNA, HelminthGene Expression RegulationIn Situ Hybridization, FluorescenceDNA, HelminthC. eleganschromosomesDNA FISHgene expressiongenome architectureOligopaint

Identifiers

PMID31084706
PMCPMC6516958
OpenAlexW2946219750

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.