Trial reportPsychiatric services (Washington, D.C.)2019
Predictors of Hospitalization of Individuals With First-Episode Psychosis: Data From a 2-Year Follow-Up of the RAISE-ETP.
Trial report in Psychiatric services (Washington, D.C.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 4 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 4 syntheses or guidelines pooled it, 47 citations in OpenAlex.
- The proportion of people with a first episode of psychosis admitted to hospital at initial presentation: a systematic review and meta-analysis.Psychological medicine · 2025Pooled it
- Specialised early intervention teams for recent-onset psychosis.The Cochrane database of systematic reviews · 2020Pooled it
- Effects of Omega 3 Fatty Acids on Main Dimensions of Psychopathology.International journal of molecular sciences · 2020Pooled it
- Polyunsaturated Fatty Acids: What is Their Role in Treatment of Psychiatric Disorders?International journal of molecular sciences · 2019Pooled it
- National and State Societal Costs of Schizophrenia in the US in 2024.JAMA psychiatry · 2026Article
- Psychiatric Hospitalization After Enrollment in Coordinated Specialty Care: Unexpected Gender- and Age-Related Disparities.Schizophrenia bulletin · 2026Article
- Psychiatric Hospitalization After Enrollment in Coordinated Specialty Care: Unexpected Gender and Age Related Disparities.medRxiv : the preprint server for health sciences · 2025Article
- Healthcare Resource Utilization 6 Months Before and After Olanzapine/Samidorphan Initiation: Real-World Assessment of Patients with Schizophrenia or Bipolar I Disorder.Advances in therapy · 2025Article
- Transdiagnostic early warning score for psychiatric hospitalisation: development and evaluation of a prediction model.BMJ mental health · 2025Article
- Automated speech and language markers of longitudinal changes in psychosis symptoms.NPP - digital psychiatry and neuroscience · 2025Article
- Exploring Data Collection Priorities of Community Partners in Early Psychosis Care.Psychiatric services (Washington, D.C.) · 2024Article
- Prevalence and predictors of admission at the time of presentation in first episode psychosis.Social psychiatry and psychiatric epidemiology · 2024Article
- Predictors of Readmission in Young Adults with First-Episode Psychosis: A Multicentric Retrospective Study with a 12-Month Follow-Up.Clinics and practice · 2024Article
- Hospitalization and help-seeking among first episode psychosis patients.Discover mental health · 2024Article
- Clinical decision-making before discharge in hospitalized persons with schizophrenia: a Spanish Delphi expert consensus.Frontiers in psychiatry · 2024Article
- Metabolic disturbances are risk factors for readmission to psychiatric hospitals in non-smokers but not in smokers: results from a Swiss psychiatric cohort and in first-episode psychosis patients.Frontiers in psychiatry · 2024Article
- Expanding Early Psychosis Care across a Large and Diverse State: Implementation Lessons Learned from Administrative Data and Clinical Team Leads in Texas.Administration and policy in mental health · 2023Article
- Early trajectory of clinical global impression as a transdiagnostic predictor of psychiatric hospitalisation: a retrospective cohort study.The lancet. Psychiatry · 2023Article
- Characterization of the extracellular free water signal in schizophrenia using multi-site diffusion MRI harmonization.Molecular psychiatry · 2023Article
- Brexpiprazole in patients with schizophrenia with or without substance use disorder: an observational study.Frontiers in psychiatry · 2023Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
objectiveDespite treatment advances in other domains, inpatient psychiatric hospitalization rates for individuals with first-episode psychosis remain high. Even with early intervention services, a third or more of individuals are hospitalized over the first 2 years of treatment. Reducing hospitalization is desirable from the individual's perspective and for public health reasons because hospitalization costs are a major component of treatment costs.
methodsUnivariate and multivariate baseline and time-varying covariate analyses were conducted to identify predictors of hospitalization in the Recovery After an Initial Schizophrenia Episode-Early Treatment Program (RAISE-ETP) study, a 2-year cluster randomized trial for participants experiencing a first episode of psychosis who were outpatients at study entry. The trial compared an early intervention treatment model (NAVIGATE) with usual community care at 34 clinics across the United States.
resultsRAISE-ETP enrolled 404 participants of whom 382 had one or more postbaseline assessments that included hospitalization data. Thirty-four percent of NAVIGATE and 37% of usual-care participants were hospitalized during the trial. Risk analyses revealed significant predictors of hospitalization to be the number of hospitalizations before study entry; duration of untreated psychosis; and time-varying days of substance misuse, presence of positive symptoms, and beliefs about the value of medication.
conclusionsThese results indicate that hospital use may be decreased by reducing the duration of untreated psychosis and prior hospitalizations, minimizing residual symptoms, preventing substance misuse, and facilitating adherence to medication taking. Addressing these factors could enhance the impact of first-episode early intervention treatment models and also enhance outcomes of people with first-episode psychosis treated using other models.
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