Evidence map›Paper›PMID 31083513›Full record

ArticleToxins2019

Effects of Subcutaneous Ochratoxin-A Exposure on Immune System of Broiler Chicks.

Shahzad Akbar Khan, Emerson J Venancio, Mario A Ono, Eduardo V Fernandes, Elisa Y Hirooka, Cleverson F Shimizu, Alexandre Oba, Karina K M C Flaiban, Eiko N Itano

Open access · goldAbstract read
In one paragraph

Article in Toxins, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.7field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Shahzad Akbar KhanDepartment of Pathologic Sciences, State University Londrina, P.O. Box 10.011, Londrina 86057-970, PR, Brazil. shahzadakbar@upr.edu.pk.ORCID 0000-0002-7431-5182
Emerson J VenancioDepartment of Pathologic Sciences, State University Londrina, P.O. Box 10.011, Londrina 86057-970, PR, Brazil. emersonj@uel.br.ORCID 0000-0002-3735-9207
Mario A OnoDepartment of Pathologic Sciences, State University Londrina, P.O. Box 10.011, Londrina 86057-970, PR, Brazil. marioono@uel.br.ORCID 0000-0002-8691-5118
Eduardo V FernandesDepartment of Pathologic Sciences, State University Londrina, P.O. Box 10.011, Londrina 86057-970, PR, Brazil. eduardovignoto@uel.br.ORCID 0000-0003-0876-2491
Elisa Y HirookaDepartment of Food Science and Technology, State University Londrina, P.O. Box 10.011, Londrina 86057-970, PR, Brazil. elisahirooka@hotmail.com.
Cleverson F ShimizuDepartment of Food Science and Technology, State University Londrina, P.O. Box 10.011, Londrina 86057-970, PR, Brazil. cvsvetuel@gmail.com.
Alexandre ObaDepartment of Zootechny, State University Londrina, P.O. Box 10.011, Londrina 86057-970, PR, Brazil. oba@uel.br.
Karina K M C FlaibanDepartment of Preventive Veterinary Medicine, State University Londrina, P.O. Box 10.011, Londrina 86057-970, PR, Brazil. kkflaiban@uel.br.
Eiko N ItanoDepartment of Pathologic Sciences, State University Londrina, P.O. Box 10.011, Londrina 86057-970, PR, Brazil. itano@uel.br.ORCID 0000-0002-0159-5494
Universidade Estadual de Londrina · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ochratoxin A (OTA), an immunosuppressive mycotoxin, can increase the risk of many infectious diseases and contribute to economic losses to the poultry industry. The immunosuppressive effect has mainly been investigated through oral exposure; however, birds may also be contaminated through skin absorption. The present study investigated the influence of OTA exposure on the defense system of broiler chicks through the subcutaneous route and including low doses. Groups of broiler chicks (Cobb), 05 days old, were exposed to subcutaneous inoculation of OTA at concentrations of 0.1; 0.5; 0.9; 1.3; and 1.7 mg OTA/kg body weight. The size of the lymphoid organs, circulating immune cells, and total IgY and IgA levels were evaluated 21 days post inoculation. Subcutaneous OTA exposure decreased the weight of the thymus, spleen, and bursa of Fabricius, and leukocytopenia (

Indexed as

AnimalsBlood ProteinsBursa of FabriciusChickensImmunoglobulin AImmunoglobulinsInjections, SubcutaneousLeukocyte CountLeukopeniaOchratoxinsSpleenThymus GlandBlood ProteinsIgYImmunoglobulin AImmunoglobulinsochratoxin AOchratoxinschicken immunoglobulinsleukocyteslymphoid organsmycotoxinpoultry

Identifiers

PMID31083513
PMCPMC6563231
OpenAlexW2945756506

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.