Evidence map›Paper›PMID 31083512›Full record

ArticleAntioxidants (Basel, Switzerland)2019

Metabolomics Studies to Assess Biological Functions of Vitamin E Nicotinate.

Lucia Marcocci, Yuichiro J Suzuki

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Metabolic Mechanism ofInternational journal of environmental research and public health · 2023
    Article
  4. Review
  5. Antioxidant Regulation of Cell Reprogramming.Antioxidants (Basel, Switzerland) · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Lucia MarcocciDepartment of Biochemical Sciences "A. Rossi Fanelli", Sapienza University of Rome, 00185 Rome, Italy. Lucia.Marcocci@uniroma1.it.ORCID 0000-0003-2301-7166
Yuichiro J SuzukiDepartment of Pharmacology and Physiology, Georgetown University Medical Center, Washington, DC 20057, USA. ys82@georgetown.edu.
Georgetown University · USSapienza University of Rome · IT

Funding

Mechanism of apoptosis in lung vascular smooth muscleR01HL072844 · NHLBI · TUFTS UNIVERSITY BOSTON · PI SUZUKI, YUICHIRO JUSTIN · 2003 to 2017
$3.3M
New mechanism of cellular protein oxidationR21AI142649 · NIAID · GEORGETOWN UNIVERSITY · PI SUZUKI, YUICHIRO JUSTIN · 2019 to 2020
$428k
Oxidant-mediated amino acid conversions in alcohol abuseR03AA026516 · NIAAA · GEORGETOWN UNIVERSITY · PI SUZUKI, YUICHIRO JUSTIN · 2019 to 2020
$156k
Endogenous protein engineering mechanismof oxidative stress in Alzheimer's diseaseR03AG059554 · NIA · GEORGETOWN UNIVERSITY · PI SUZUKI, YUICHIRO JUSTIN · 2018 to 2019
$156k
National Institutes of Health R01HL072844, R21AI142649, R03AG059554, and R03AA026516NHLBI NIH HHS R01 HL072844NIAAA NIH HHS R03 AA026516NIAID NIH HHS R21 AI142649NIA NIH HHS R03 AG059554
6 · The paper itself

Abstract

Vitamin E nicotinate (tocopherol nicotinate, tocopheryl nicotinate; TN) is an ester of two vitamins, tocopherol (vitamin E) and niacin (vitamin B3), in which niacin is linked to the hydroxyl group of active vitamin E. This vitamin E ester can be chemically synthesized and is used for supplementation. However, whether TN is formed in the biological system was unclear. Our laboratory previously detected TN in rat heart tissues, and its level was 30-fold lower in a failing heart (Wang et al.,

Indexed as

cell signalingtocopherol nicotinatetocopheryl nicotinatevitamin E nicotinate

Identifiers

PMID31083512
PMCPMC6562962
OpenAlexW2944069665

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.