Evidence map›Paper›PMID 31083509›Full record

ReviewPathogens (Basel, Switzerland)2019

Hepatitis B Virus Molecular Epidemiology, Host-Virus Interaction, Coinfection, and Laboratory Diagnosis in the MENA Region: An Update.

Duaa W Al-Sadeq, Sara A Taleb, Roan E Zaied, Sara M Fahad, Maria K Smatti, Balsam R Rizeq, Asmaa A Al Thani, Hadi M Yassine, Gheyath K Nasrallah

Open access · goldAbstract readReview
In one paragraph

Review in Pathogens (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Aptamer-based biosensors for virus protein detection.Trends in analytical chemistry : TRAC · 2022
    Review
  13. Article
  14. Hepatitis B and circadian rhythm of the liver.World journal of gastroenterology · 2022
    Review
  15. Review
  16. Article
  17. The Role of Bcl-xL Protein in Viral Infections.International journal of molecular sciences · 2021
    Review
  18. Hepatitis B Virus: From Diagnosis to Treatment.Polish journal of microbiology · 2020
    Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Duaa W Al-SadeqBiomedical Research Center, Qatar University, Doha 2713, Qatar. da1206066@qu.edu.qa.
Sara A TalebBiomedical Science Department, College of Health Sciences, Qatar University, Doha 2713, Qatar. st1000813@student.qu.edu.qa.ORCID 0000-0003-1795-0064
Roan E ZaiedBiomedical Science Department, College of Health Sciences, Qatar University, Doha 2713, Qatar. rz1407001@student.qu.edu.qa.
Sara M FahadBiomedical Research Center, Qatar University, Doha 2713, Qatar. 200452443@student.qu.edu.qa.
Maria K SmattiBiomedical Research Center, Qatar University, Doha 2713, Qatar. msmatti@qu.edu.qa.ORCID 0000-0002-7621-0130
Balsam R RizeqBiomedical Research Center, Qatar University, Doha 2713, Qatar. brizeq@qu.edu.qa.
Asmaa A Al ThaniBiomedical Research Center, Qatar University, Doha 2713, Qatar. aaja@qu.edu.qa.
Hadi M YassineBiomedical Research Center, Qatar University, Doha 2713, Qatar. hyassine@qu.edu.qa.ORCID 0000-0001-7592-2788
Gheyath K NasrallahBiomedical Research Center, Qatar University, Doha 2713, Qatar. gheyath.nasrallah@qu.edu.qa.ORCID 0000-0001-9252-1038
Qatar University · QA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatitis B virus (HBV) is an enveloped partial double-stranded DNA virus that can cause acute and chronic hepatitis. According to the World Health Organization (WHO) and the Centers for Disease Control and Prevention (CDC), 257 million people are living with HBV. Moreover, 20,900 acute hepatitis B cases were reported in 2016. Hepatitis B is highly prevalent in the African, Western Pacific, Eastern Mediterranean, South-East Asia, and European regions, respectively. Due to the high mutational rate of HBV and lack of reverse transcriptase proofreading activity, ten different genotypes with different geographical distributions have been identified. HBV pathogenesis and severity of infection depend on several host and viral factors, particularly, the genetic variability of both the host and virus. Although HBV infection is a global health concern, there is a lack of adequate studies and reports in the Middle East and North Africa (MENA) region. Here, we provide a review on HBV epidemiology, pathogenesis, host-pathogen interactions, coinfection with selected viruses, and laboratory diagnosis, focusing on studies conducted in the MENA region to determine the current situation of the HBV infection and outline the future study areas.

Indexed as

genotypesHBVpathogenesisseroprevalencetransfusionviremia

Identifiers

PMID31083509
PMCPMC6630671
OpenAlexW2944054652

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.