Evidence map›Paper›PMID 31083436›Full record

ArticleInternational journal of environmental research and public health2019

Sickle Cell Anaemia Prevalence Among Newborns in the Brazilian Amazon-Savanna Transition Region.

Rayane Cristina Souza, Pedro Agnel Dias Miranda Neto, Jessflan Rafael Nascimento Santos, Sílvio Gomes Monteiro, Maria Cláudia Gonçalves, Fabrício Brito Silva, Rodrigo Assuncao Holanda, Julliana Ribeiro Alves Santos

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Rayane Cristina SouzaBiomédica and Mestranda em Meio Ambiente da Universidade CEUMA, São Luís, MA, CEP: 65075-120, Brazil. naume.rayane@hotmail.com.
Pedro Agnel Dias Miranda NetoFaculdade Pitágoras, São Luís, MA, CEP: 65075-120, Brazil. pedroagnelneto@gmail.com.
Jessflan Rafael Nascimento SantosLaboratório de Geotecnologias, Universidade CEUMA, São Luís, MA, CEP: 65075-120, Brazil. jessflan@ymail.com.
Sílvio Gomes MonteiroMestrado em Meio Ambiente da Universidade CEUMA, São Luís, MA, CEP: 65075-120, Brazil. silvio_gm@yahoo.com.br.
Maria Cláudia GonçalvesMestrado em Meio Ambiente da Universidade CEUMA, São Luís, MA, CEP: 65075-120, Brazil. mcgfisio0@gmail.com.
Fabrício Brito SilvaMestrado em Meio Ambiente da Universidade CEUMA, São Luís, MA, CEP: 65075-120, Brazil. fabricioagro@gmail.com.
Rodrigo Assuncao HolandaMestrado em Biologia Microbiana da Universidade CEUMA, São Luís, MA, CEP: 65075-120, Brazil. raholanda@yahoo.com.br.
Julliana Ribeiro Alves SantosMestrado em Meio Ambiente e Mestrado em Biologia Microbiana da Universidade CEUMA, São Luís, MA, CEP: 65075-120, Brazil. jullianarasantos01@gmail.com.
Universidade Ceuma · BRGeotecno (Brazil) · BRFaculdades Oswaldo Cruz · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sickle cell anaemia is one of the most common hemoglobinopathies worldwide and an important public health problem in Brazil. This study evaluated the prevalence of sickle cell anaemia and its traits in newborns from the Amazon-Savanna Transition Region in the state of Maranhão, Brazil. A cross-sectional study was carried out, based on data from neonatal screening tests performed in 2013-2015 in Maranhão. The Hardy-Weinberg theorem was applied to analyse the frequency of expected homozygotes based on HbSS phenotype. A spatial-temporal distribution analysis was performed to delimit the regions with the greatest number of newborn cases with sickle cell anaemia. Of 283,003 newborns, 162 were found to have sickle cell anaemia, while 10,794 had a sickle cell trait, with a prevalence of 0.05% and 3.8%, respectively. The prevalence of expected homozygotes was higher in the North Region and in the state capital of Maranhão. This study may contribute to existing social and public health actions or the creation of new strategies for sickle cell disease in endemic areas in Brazil to improve the quality of life.

Indexed as

EnvironmentAnemia, Sickle CellBrazilCross-Sectional StudiesFemaleForestsGrasslandHumansInfant, NewbornMaleNeonatal ScreeningPrevalenceepidemiologysickle cell anaemiaspatio-temporal distribution

Identifiers

PMID31083436
PMCPMC6540180
OpenAlexW2944240457

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.