Evidence map›Paper›PMID 31083300›Full record

ArticleInternational journal of molecular sciences2019

3-Methylcholanthrene Induces Chylous Ascites in TCDD-Inducible Poly-ADP-Ribose Polymerase (

Tiffany E Cho, Debbie Bott, Shaimaa Ahmed, David Hutin, Alvin Gomez, Laura Tamblyn, Angela C Zhou, Tania H Watts, Denis M Grant, Jason Matthews

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. The aryl hydrocarbon receptor: a new frontier in male reproductive system.Reproductive biology and endocrinology : RB&E · 2025
    Review
  2. Review
  3. Article
  4. Review
  5. Novel Aspects of Toxicity Mechanisms of Dioxins and Related Compounds.International journal of molecular sciences · 2020
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Tiffany E ChoDepartment of Pharmacology and Toxicology, University of Toronto, Toronto, ON M5S 1A8, Canada. tiffany.cho@mail.utoronto.ca.
Debbie BottDepartment of Pharmacology and Toxicology, University of Toronto, Toronto, ON M5S 1A8, Canada. debb.bott@gmail.com.
Shaimaa AhmedDepartment of Pharmacology and Toxicology, University of Toronto, Toronto, ON M5S 1A8, Canada. shaimaa.ahmed1@gmail.com.
David HutinDepartment of Pharmacology and Toxicology, University of Toronto, Toronto, ON M5S 1A8, Canada. dhutin1@gmail.com.
Alvin GomezDepartment of Pharmacology and Toxicology, University of Toronto, Toronto, ON M5S 1A8, Canada. alvin_v_gomez@yahoo.com.
Laura TamblynDepartment of Pharmacology and Toxicology, University of Toronto, Toronto, ON M5S 1A8, Canada. Laura.Tamblyn@uhnresearch.ca.
Angela C ZhouDepartment of Immunology, University of Toronto, Toronto, ON M5S 1A8, Canada. angel.zhou@mail.utoronto.ca.
Tania H WattsDepartment of Immunology, University of Toronto, Toronto, ON M5S 1A8, Canada. tania.watts@utoronto.ca.
Denis M GrantDepartment of Pharmacology and Toxicology, University of Toronto, Toronto, ON M5S 1A8, Canada. denis.grant@utoronto.ca.
Jason MatthewsDepartment of Pharmacology and Toxicology, University of Toronto, Toronto, ON M5S 1A8, Canada. Jason.matthews@medisin.uio.no.ORCID 0000-0002-9815-8636
University of Toronto · CAUniversity of Oslo · NO

Funding

Canadian Institutes of Health Research MOP-494265 and MOP-125919Johan Throne Holst Foundation 710845Unrestricted research grant from the DOW Chemical Company no number
6 · The paper itself

Abstract

TCDD-inducible poly-ADP-ribose polymerase (TIPARP) is an aryl hydrocarbon receptor (AHR) target gene that functions as part of a negative feedback loop to repress AHR activity.

Indexed as

Adipose TissueAnimalsAzo CompoundsChylous AscitesCytokinesFatty LiverGene Expression Regulation, EnzymologicInflammationInflammation MediatorsLiverMaleMethylcholanthreneMice, KnockoutPoly(ADP-ribose) PolymerasesPolychlorinated DibenzodioxinsPyrazoles2,3,7,8-tetrachlorodibenzo-p-dioxin poly(ADP-ribose) polymerase, mouse2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amideAzo CompoundsCytokinesInflammation MediatorsMethylcholanthrenePoly(ADP-ribose) PolymerasesPolychlorinated DibenzodioxinsPyrazolesReceptors, Aryl Hydrocarbon2,3,7,8-tetrachlorodibenzo-p-dioxin3-methylcholanthrenechylous ascitesTCDD-inducible poly-ADP-ribose polymerase (TIPARP)wasting syndrome

Identifiers

PMID31083300
PMCPMC6540065
OpenAlexW2943937092

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.