Evidence map›Paper›PMID 31083233›Full record

ArticleMedicine2019

Diagnostic efficacy of smear plus liquid-based cytology for EUS-FNA of solid pancreatic lesions: A propensity-matched study.

Masahiro Itonaga, Shin-Ichi Murata, Keiichi Hatamaru, Takashi Tamura, Junya Nuta, Yuki Kawaji, Takao Maekita, Mikitaka Iguchi, Jun Kato, Fumiyoshi Kojima and 7 more

Abstract readComparative Study
In one paragraph

Article in Medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
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  6. Article
  7. Article
  8. Cancers · 2022
    Article
  9. Review
  10. Article
  11. Article
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  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Masahiro ItonagaSecond Department of Internal Medicine.
Shin-Ichi MurataDepartment of Human Pathology.
Keiichi HatamaruSecond Department of Internal Medicine.
Takashi TamuraSecond Department of Internal Medicine.
Junya NutaSecond Department of Internal Medicine.
Yuki KawajiSecond Department of Internal Medicine.
Takao MaekitaSecond Department of Internal Medicine.
Mikitaka IguchiSecond Department of Internal Medicine.
Jun KatoSecond Department of Internal Medicine.
Fumiyoshi KojimaDepartment of Human Pathology.
Hiroki YamaueSecond Department of Surgery.
Manabu KawaiSecond Department of Surgery.
Ken-Ichi OkadaSecond Department of Surgery.
Seiko HironoSecond Department of Surgery.
Toshio ShimokawaClinical Study Support Center, Wakayama Medical University, Wakayama, Japan.
Kensuke TaniokaClinical Study Support Center, Wakayama Medical University, Wakayama, Japan.
Masayuki KitanoSecond Department of Internal Medicine.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Liquid-based cytology (LBC) is a thin-layer slide preparation procedure that was developed to overcome the cell crowding and contamination associated with smear cytology (SC). The present study compared diagnostic efficacy between SC alone and SC combined with LBC (SLBC) using endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) samples of pancreatic lesions.We retrospectively analyzed data derived from 311 consecutive patients. Specimens obtained via EUS-FNA from 179 patients between December 2011 and May 2016 were analyzed by SC, and those obtained from 132 patients between June 2016 and October 2017 were analyzed by SLBC. The 2 groups were compared in terms of adequate sample rate, diagnostic accuracy, sensitivity, and specificity using propensity score matching.SC and SLBC were compared using propensity score-matching in 204 patients (n = 102 per group). The adequate sample rate did not differ significantly between SLBC (100%) and SC (99.0%, P = 1). Diagnostic sensitivity, negative predictive value and accuracy were better for SLBC than for SC in terms of cytological (93.2% vs 67.4%, 68.4% vs 23.1%, and 94.1% vs 69.6%, P < .01 each, respectively) and cytohistological (95.5% vs 81.5%, 76.5% vs 34.6%, and 96.1% vs 82.4%, P < .01, P = .02, and P < .01, respectively) analyses.SLBC improves the diagnostic efficacy of EUS-FNA for pancreatic lesions compared to LBC.

Indexed as

AdultAgedAged, 80 and overEndoscopic Ultrasound-Guided Fine Needle AspirationFemaleHumansMaleMiddle AgedPancreasPancreatic DiseasesPropensity ScoreRetrospective StudiesSensitivity and Specificity

Identifiers

PMID31083233
PMCPMC6531231

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.