ReviewHarvard review of psychiatry
The Emerging Empirical Science of Wisdom: Definition, Measurement, Neurobiology, Longevity, and Interventions.
Review in Harvard review of psychiatry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed.
- Shifting from brain ageing to brain longevity.Nature human behaviour · 2026Article
- The role of brain health and resilience in reshaping trajectories of late-life neuropsychiatric disorders.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Review
- Bio-inspired cognitive robotics vs. embodied AI for socially acceptable, civilized robots.Frontiers in robotics and AI · 2026Article
- The virtue of temperance: a neurobiological perspective.Frontiers in human neuroscience · 2026Article
- The coming era of proteomics-driven precision medicine.National science review · 2025Review
- Mutual human-robot understanding for a robot-enhanced society: the crucial development of shared embodied cognition.Frontiers in artificial intelligence · 2025Review
- Protective factors of prenatal depression, anxiety and stress: a network analysis of Bernstein's strengths model.Frontiers in psychiatry · 2025Article
- Emotional needs for smart products: a case study of older people living alone in Chengdu, China.Frontiers in psychology · 2025Article
- Finding the Balance to Quiet the Striving: The Difference Between Successful Aging and Wise Aging.The Gerontologist · 2024Article
- Article
- Wisdom affinity in the general population.BMC psychology · 2024Article
- Adult age-related differences in susceptibility to social conformity pressures in self-control over daily desires.Psychology and aging · 2024Article
- Clinical Practice Guidelines on using artificial intelligence and gadgets for mental health and well-being.Indian journal of psychiatry · 2024Article
- Latent subgroups with distinct patterns of factors associated with self-rated successful aging among 1,510 community-dwelling Americans: potential role of wisdom as an implicit promoter.Aging & mental health · 2023Article
- The Microbiome and Mental Health Across the Lifespan.Current topics in behavioral neurosciences · 2023Article
- Abbreviated San Diego Wisdom Scale (SD-WISE-7) and Jeste-Thomas Wisdom Index (JTWI).International psychogeriatrics · 2022Article
- Artificial intelligence and Psychiatry: An overview.Asian journal of psychiatry · 2022Review
- Wisdom and fluid intelligence are dissociable in healthy older adults.International psychogeriatrics · 2022Article
- Wisdom: Meaning, structure, types, arguments, and future concerns.Current psychology (New Brunswick, N.J.) · 2022Article
- Neuroimaging-derived brain age is associated with life satisfaction in cognitively unimpaired elderly: A community-based study.Translational psychiatry · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
LEARNING
objectivesAfter participating in this activity, learners should be better able to:• Assess the empirical literature on wisdom• Evaluate a proposed model of wisdom development ABSTRACT: This article seeks to provide an overview of the empirical literature on wisdom in terms of its definitions and measurements, possible neurobiological basis, and evolutionary value, as well as changes with aging and potential clinical interventions to enhance components of wisdom. Wisdom may be defined as a complex human trait with several specific components: social decision making, emotion regulation, prosocial behaviors, self-reflection, acceptance of uncertainty, decisiveness, and spirituality. These components appear to be localized primarily to the prefrontal cortex and limbic striatum. Emerging research suggests that wisdom is linked to better overall health, well-being, happiness, life satisfaction, and resilience. Wisdom likely increases with age, facilitating a possible evolutionary role of wise grandparents in promoting the fitness of the species. Despite the loss of their own fertility and physical health, older adults help enhance their children's well-being, health, longevity, and fertility-the "Grandma Hypothesis" of wisdom. We propose a model of wisdom development that incorporates genetic, environmental, and evolutionary aspects. Wisdom has important implications at both individual and societal levels, and warrants further research as a major contributor to human thriving. There is a need for a greater emphasis on promoting wisdom through our educational systems from elementary to professional schools.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.