Evidence map›Paper›PMID 31082633›Full record

ReviewCurrent opinion in cell biology2019

Spindle assembly and chromosome dynamics during oocyte meiosis.

Timothy J Mullen, Amanda C Davis-Roca, Sarah M Wignall

Abstract readReview
In one paragraph

Review in Current opinion in cell biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed.

  1. Article
  2. Article
  3. PMEnvironment & health (Washington, D.C.) · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Timothy J MullenDepartment of Molecular Biosciences, Northwestern University, Evanston, IL 60208, United States.
Amanda C Davis-RocaDepartment of Molecular Biosciences, Northwestern University, Evanston, IL 60208, United States.
Sarah M WignallDepartment of Molecular Biosciences, Northwestern University, Evanston, IL 60208, United States. Electronic address: s-wignall@northwestern.edu.

Funding

CARCINOGENESIS TRAINING PROGRAMT32CA009560 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Kathleen Janee Green · 1986 to 2026
$8.4M
Regulation of chromosome segregation during oocyte meiosisR01GM124354 · NIGMS · NORTHWESTERN UNIVERSITY · PI SARAH Marie WIGNALL · 2018 to 2026
$2.8M
NCI NIH HHS T32 CA009560NIGMS NIH HHS R01 GM124354
6 · The paper itself

Abstract

Organisms that reproduce sexually utilize a specialized form of cell division called meiosis to reduce their chromosome number by half to generate haploid gametes. Meiosis in females is especially error-prone, and this vulnerability has a profound impact on human health: it is estimated that 10-25% of human embryos are chromosomally abnormal, and the vast majority of these defects arise from problems with the female reproductive cells (oocytes). Here, we highlight recent studies that explore how these important cells divide. Although we focus on work in the model organism Caenorhabditis elegans, we also discuss complementary studies in other organisms that together provide new insights into this crucial form of cell division.

Indexed as

MeiosisAnimalsCaenorhabditis elegansChromosomesChromosome SegregationModels, BiologicalOocytesSpindle Apparatus

Identifiers

PMID31082633
PMCPMC6756943

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.