Evidence map›Paper›PMID 31081985›Full record

ArticleAmerican journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics2019

Genome-wide analyses of psychological resilience in U.S. Army soldiers.

Murray B Stein, Karmel W Choi, Sonia Jain, Laura Campbell-Sills, Chia-Yen Chen, Joel Gelernter, Feng He, Steven G Heeringa, Adam X Maihofer, Caroline Nievergelt and 6 more

Open access · bronzeAbstract read
In one paragraph

Article in American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 2 pooled it
8.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 2 syntheses or guidelines pooled it, 55 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Transdiagnostic prevention in youth mental health, Part I: rationale, shared risk factors.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Review
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  10. Associations between polygenic liability to psychopathology and non-suicidal versus suicidal self-injury.American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics · 2024
    Article
  11. Article
  12. Article
  13. A statistical genetic investigation of psychiatric resilience.European journal of psychotraumatology · 2023
    Article
  14. Article
  15. Review
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 7 institutions in 2 countries.

Murray B SteinDepartment of Psychiatry, University of California San Diego, La Jolla, California.ORCID 0000-0001-9564-2871
Karmel W ChoiPsychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, Massachusetts.
Sonia JainDepartment of Family Medicine and Public Health, University of California San Diego, La Jolla, California.
Laura Campbell-SillsDepartment of Psychiatry, University of California San Diego, La Jolla, California.
Chia-Yen ChenPsychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, Massachusetts.
Joel GelernterDepartment of Psychiatry, Yale University, New Haven, Connecticut.
Feng HeDepartment of Family Medicine and Public Health, University of California San Diego, La Jolla, California.
Steven G HeeringaInstitute for Social Research, University of Michigan, Ann Arbor, Michigan.
Adam X MaihoferDepartment of Psychiatry, University of California San Diego, La Jolla, California.
Caroline NievergeltDepartment of Psychiatry, University of California San Diego, La Jolla, California.
Matthew K NockDepartment of Psychology, Harvard University, Cambridge, Massachusetts.
Stephan RipkeStanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts.
Xiaoying SunDepartment of Family Medicine and Public Health, University of California San Diego, La Jolla, California.
Ronald C KesslerDepartment of Health Care Policy, Harvard Medical School, Boston, Massachusetts.
Jordan W SmollerPsychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, Massachusetts.
Robert J UrsanoDepartment of Psychiatry, Uniformed Services University of the Health Sciences, Bethesda, Maryland.
University of California San Diego · USBroad Institute · USHarvard University · USMassachusetts General Hospital · USUniformed Services University of the Health Sciences · USUniversity of Michigan · USYale University · US

Funding

Modifiable Risk and Protective Factors for Suicidal Behaviors in the US ArmyU01MH087981 · NIMH · HENRY M. JACKSON FDN FOR THE ADV MIL/MED · PI STEIN, MURRAY B., URSANO, ROBERT J. · 2009 to 2013
$65.0M
Training Program in Psychiatric Genetics and Translational ResearchT32MH017119 · NIMH · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI KARESTAN C KOENEN, Jukka-Pekka Onnela · 1985 to 2026
$8.9M
Psychiatric Genomics Consortium for PTSDR01MH106595 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI KARESTAN C KOENEN, Caroline M Nievergelt · 2016 to 2026
$8.4M
Research and Mentoring on Integrating Psychiatric Genetics and NeuroscienceK24MH094614 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI SMOLLER, JORDAN W · 2012 to 2016
$925k
NIMH NIH HHS K24 MH094614NIMH NIH HHS R01 MH106595NIMH NIH HHS T32 MH017119NIMH NIH HHS U01 MH087981
6 · The paper itself

Abstract

Though a growing body of preclinical and translational research is illuminating a biological basis for resilience to stress, little is known about the genetic basis of psychological resilience in humans. We conducted genome-wide association studies (GWASs) of self-assessed (by questionnaire) and outcome-based (incident mental disorders from predeployment to postdeployment) resilience among European (EUR) ancestry soldiers in the Army study to assess risk and resilience in servicemembers. Self-assessed resilience (N = 11,492) was found to have significant common-variant heritability (h

Indexed as

Resilience, PsychologicalAdaptation, PsychologicalAdultAnxiety DisordersFemaleGenetic Predisposition to DiseaseGenome-Wide Association StudyHumansMaleMilitary PersonnelMultifactorial InheritanceStress Disorders, Post-TraumaticUnited StatesWhite Peoplegeneticsgenome-wide associationmental disorderresiliencerisk

Identifiers

PMID31081985
PMCPMC6551278
OpenAlexW2952129742

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.