Observational studyJournal of the American Medical Informatics Association : JAMIA2019
Count me in: using a patient portal to minimize implicit bias in clinical research recruitment.
Observational study in Journal of the American Medical Informatics Association : JAMIA, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The usage of population and disease registries as pre-screening tools for clinical trials, a systematic review.Systematic reviews · 2024Pooled it
- Impact of Financial Incentives on Electronic Health Record-Driven Recruitment of Underrepresented Communities in Research: Randomized Controlled Trial.Journal of medical Internet research · 2026Trial
- Patient and carer perceptions and experiences of technology-facilitated appointment reminders in healthcare: a scoping review.Journal of the American Medical Informatics Association : JAMIA · 2026Article
- "What's the fun in That?": Latinx Families' Facilitators and Barriers to Virtual Research Participation.Hispanic health care international : the official journal of the National Association of Hispanic Nurses · 2025Article
- Inclusion and reporting by age, sex, and ethnicity in clinical studies of high-risk medical devices approved in the European Union.European heart journal. Quality of care & clinical outcomes · 2025Article
- Severe-to-Profound Hearing Loss and Mental Health: Initial Evidence That Cochlear Implantation Helps Alleviate Symptoms of Anxiety and Stress.Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery · 2025Article
- Decentralized subject recruitment for a prospective community surveillance system: The influence of social determinants of health on inclusion of minorities in research.Journal of clinical and translational science · 2025Article
- Willingness to Be Contacted via a Patient Portal for Health Screening, Research Recruitment, and at-Home Self-Test Kits for Health Monitoring: Pilot Quantitative Survey.JMIR formative research · 2024Article
- Wearable Devices, Health Care Use, and Psychological Well-Being in Patients With Atrial Fibrillation.Journal of the American Heart Association · 2024Article
- Article
- Strategies for enhancing the representation of women in clinical trials: an evidence map.Systematic reviews · 2024Article
- Implementation ofJournal of clinical and translational science · 2024Article
- Pilot training for clinical research professionals in using empathy to recognize and respond to implicit bias in research recruitment and retention.Journal of clinical and translational science · 2024Article
- Embedding research study recruitment within the patient portal preCheck-in.Journal of the American Medical Informatics Association : JAMIA · 2023Article
- Design, implementation, and inferential issues associated with clinical trials that rely on data in electronic medical records: a narrative review.BMC medical research methodology · 2023Review
- Enhancing study recruitment through implementation of an opt-out, cold contact process with consideration for autonomy, beneficence and justice.Journal of clinical and translational science · 2023Article
- Using a patient portal as a recruitment tool to diversify the pool of participants in COVID-19 vaccine clinical trials.JAMIA open · 2022Article
- Article
- Building trust in research through information and intent transparency with health information: representative cross-sectional survey of 502 US adults.Journal of the American Medical Informatics Association : JAMIA · 2022Article
- Using a Patient Portal to Increase Enrollment in a Newborn Screening Research Study: Observational Study.JMIR pediatrics and parenting · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
Abstract
objectiveDetermine whether women and men differ in volunteering to join a Research Recruitment Registry when invited to participate via an electronic patient portal without human bias. MATERIALS AND
methodsUnder-representation of women and other demographic groups in clinical research studies could be due either to invitation bias (explicit or implicit) during screening and recruitment or by lower rates of deciding to participate when offered. By making an invitation to participate in a Research Recruitment Registry available to all patients accessing our patient portal, regardless of demographics, we sought to remove implicit bias in offering participation and thus independently assess agreement rates.
resultsWomen were represented in the Research Recruitment Registry slightly more than their proportion of all portal users (n = 194 775). Controlling for age, race, ethnicity, portal use, chronic disease burden, and other questionnaire use, women were statistically more likely to agree to join the Registry than men (odds ratio 1.17, 95% CI, 1.12-1.21). In contrast, Black males, Hispanics (of both sexes), and particularly Asians (both sexes) had low participation-to-population ratios; this under-representation persisted in the multivariable regression model. DISCUSSION: This supports the view that historical under-representation of women in clinical studies is likely due, at least in part, to implicit bias in offering participation. Distinguishing the mechanism for under-representation could help in designing strategies to improve study representation, leading to more effective evidence-based recommendations.
conclusionPatient portals offer an attractive option for minimizing bias and encouraging broader, more representative participation in clinical research.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.