Evidence map›Paper›PMID 31081754›Full record

ArticleeLife2019

A combination of transcription factors mediates inducible interchromosomal contacts.

Seungsoo Kim, Maitreya J Dunham, Jay Shendure

Open access · goldAbstract read
In one paragraph

Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Long-distance association of topological boundaries through nuclear condensates.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Seungsoo KimDepartment of Genome Sciences, University of Washington, Seattle, United States.ORCID 0000-0002-5559-5289
Maitreya J DunhamDepartment of Genome Sciences, University of Washington, Seattle, United States.ORCID 0000-0001-9944-2666
Jay ShendureDepartment of Genome Sciences, University of Washington, Seattle, United States.ORCID 0000-0002-1516-1865
University of Washington · USHoward Hughes Medical Institute · US

Funding

University of Washington Center for Nuclear Organization and FunctionU54DK107979 · NIDDK · UNIVERSITY OF WASHINGTON · PI NOBLE, WILLIAM STAFFORD, SHENDURE, JAY ASHOK · 2015 to 2019
$11.8M
Howard Hughes Medical Institute InvestigatorNIDDK NIH HHS U54 DK107979NIH HHS U54 DK107979
6 · The paper itself

Abstract

The genome forms specific three-dimensional contacts in response to cellular or environmental conditions. However, it remains largely unknown which proteins specify and mediate such contacts. Here we describe an assay, MAP-C (Mutation Analysis in Pools by Chromosome conformation capture), that simultaneously characterizes the effects of hundreds of

Indexed as

Chromosomes, FungalDNA-Binding ProteinsMutationProtein BindingSaccharomycesSaccharomyces cerevisiae ProteinsTrans-ActivatorsTranscription FactorsTranscription Factors, GeneralDNA-Binding ProteinsLEU3 protein, S cerevisiaeRGT1 protein, S cerevisiaeSaccharomyces cerevisiae ProteinsSDD4 protein, S cerevisiaeTrans-ActivatorsTranscription FactorsTranscription Factors, General3Cchromosome conformationchromosomesgene expressiongeneticsgenomicshomolog pairingmutational scanningsaturation mutagenesisS. cerevisiaetranscription factors

Identifiers

PMID31081754
PMCPMC6548505
OpenAlexW2950296551

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.