ArticleEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2019
Significant variation in heart valve banking practice.
Article in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed.
- 20-year analysis of protocol-driven quality improvement in cardiac homograft banking.Cell and tissue banking · 2026Article
- Comparing the efficacy of two antibiotic cocktails in decontamination of cardiovascular tissues.Cell and tissue banking · 2025Article
- Risk of tuberculosis transmission by tissue transplantation: a quantitative risk assessment.Cell and tissue banking · 2025Article
- Setting up an external quality assessment scheme to assess the effectiveness of microbiology testing currently carried out in heart valve banking.Cell and tissue banking · 2025Article
- Last twenty-years activity of cardiovascular tissue banking in Barcelona.Cell and tissue banking · 2024Article
- Impact of storage time prior to cryopreservation on mechanical properties of aortic homografts.Cell and tissue banking · 2024Article
- Transplantation of cryopreserved human heart valves in Europe: 30 years of banking in Brussels and future perspectives.Cell and tissue banking · 2021Review
- Does microbiological contamination of homografts prior to decontamination affect the outcome after right ventricular outflow tract reconstruction?Interactive cardiovascular and thoracic surgery · 2021Article
- Impact of valve fenestrations and structural changes in homografts on the long-term outcome in the recipient.Cell and tissue banking · 2021Article
- The time has come to extend the expiration limit of cryopreserved allograft heart valves.Cell and tissue banking · 2021Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The European Blood Alliance (EBA) Tissue and Cells annual benchmarking exercise identified that in 2014, the heart valve (HV) discard rate in tissue establishments (TEs) run by EBA members was between 19 and 65%. Given this significant discard rate, a decision was taken to carry out a worldwide data-gathering exercise to assess the processing methodology in different TEs. In collaboration with the Foundation of European Tissue Banks, a questionnaire asking for the details on HV processing was sent to TEs worldwide. Nineteen questionnaires were received back from 15 European TEs and 4 non-European TEs. The data provided confirmed a significant discard rate of HVs with 43-50% of aortic valves and 20-32% of pulmonary valves being discarded in 2015. The causes of HV discard varied, with microbiology contamination, anatomical and medical reasons being the main causes. This data-gathering exercise highlighted significant variations in practice in different TEs including how donor suitability is assessed, critical timings for heart retrieval and processing, heart rinsing, HV decontamination protocols and methods of microbiological testing. To reduce the discard rates, there are several aspects of HV banking that could be validated and standardised. Here, we report the findings of this data-gathering exercise. We consider this a first step that will help lead to standardising HV banking.
Indexed as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.