ArticleEuropean journal of pediatrics2019
The triglycerides and glucose index is associated with elevated blood pressure in apparently healthy children and adolescents.
Article in European journal of pediatrics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.
- Association between triglyceride-glucose index and hypertension: A systematic review and meta-analysis.Narra J · 2024Pooled it
- Triglyceride-glucose index and abnormal blood pressure in adults aged over 70 years: real-world data evidence.BMC cardiovascular disorders · 2026Article
- Blood Pressure Levels and Triglyceride-Glucose Index: A Cross-Sectional Study from a Nationwide Screening in Mongolia.Journal of clinical medicine · 2025Article
- Article
- Association between TyG-BMI and early-onset hypertension: evidence from NHANES.Scientific reports · 2025Article
- Metabolic transition from childhood to adulthood based on two decades of biochemical time series in three longitudinal cohorts.International journal of epidemiology · 2025Article
- U-shaped association between triglyceride-glucose index and acute kidney injury in critically ill children with cardiac diseases.Frontiers in endocrinology · 2025Article
- Dynamic trajectories of the triglyceride-glucose index link to all-cause hospital mortality in patients with hypertension and kidney failure: a multicenter study.Frontiers in endocrinology · 2025Article
- Associations of triglyceride-glucose index and metabolic score for insulin resistance with various hypertension phenotypes in children and adolescents: results from the 2017 China nutrition and health surveillance.Frontiers in endocrinology · 2025Article
- Elevated triglyceride-glucose index is a risk factor for progression to prehypertension in normoglycemic Japanese: a 5-year retrospective cohort study.Clinical hypertension · 2024Article
- Weight Gain from Birth to Adolescence and TyG Index at Age 18 Years: A Cohort Study in Northeast Brazil.Maternal and child health journal · 2024Article
- Central and peripheral blood pressures in relation to the triglyceride-glucose index in a Chinese population.Cardiovascular diabetology · 2024Article
- The effect of insulin resistance in the association between obesity and hypertension incidence among Chinese middle-aged and older adults: data from China health and retirement longitudinal study (CHARLS).Frontiers in public health · 2024Article
- Association between the triglyceride glucose index and the risk of acute kidney injury in critically ill patients with hypertension: analysis of the MIMIC-IV database.Frontiers in endocrinology · 2024Article
- Triglyceride-glucose index is associated with hypertension incidence up to 13 years of follow-up in mexican adults.Lipids in health and disease · 2023Article
- The relationship and interaction between triglyceride glucose index and obesity in the risk of prehypertension population: a cross-sectional study from a survey in Anhui, Eastern China.BMC cardiovascular disorders · 2023Article
- Association of the triglycerides and glucose index and the homeostatic model assessment of insulin resistance with lipoprotein(a), apolipoprotein AI, and apolipoprotein B concentrations in children with normal-weight.European journal of pediatrics · 2023Article
- Positive association of triglyceride-glucose index with new-onset hypertension among adults: a national cohort study in China.Cardiovascular diabetology · 2023Article
- High Triglyceride-Glucose Index Is Associated with Poor Prognosis in Patients with Acute Pancreatitis.Digestive diseases and sciences · 2023Article
- Role of Insulin Resistance as a Mediator of the Relationship between Body Weight, Waist Circumference, and Systolic Blood Pressure in a Pediatric Population.Metabolites · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Prevalence of elevated blood pressure in pediatric population has been increasing worldwide. Thus, the aim of this study was to examine whether the triglycerides and glucose (TyG) index is associated with the presence of prehypertension or hypertension in children and adolescents. Apparently healthy children aged 6 to 15 years were enrolled in a population-based cross-sectional study. Participants were allocated into groups with normal blood pressure (NBP), prehypertension, and hypertension. Smoking, alcohol intake, pregnancy, previous diagnosis of diabetes, kidney, hepatic, or endocrine diseases were exclusion criteria. NBP was defined by systolic and/or diastolic blood pressure < 90th percentile, prehypertension by systolic and/or diastolic blood pressure ≥ 90th < 95th percentile, and hypertension by systolic and/or diastolic blood pressure ≥ 95th percentile, according to age, sex, and height percentiles. A total of 3589 children were enrolled, 1748 (49%) girls and 1841 (51%) boys, and allocated into groups with NBP (n = 2874), prehypertension (n = 271), and hypertension (n = 444). The multiple logistic regression analysis stratified by age and adjusted by the Z-score/SDS of body mass index and waist circumference showed that elevated TyG index was significantly associated with prehypertension (OR = 1.48; 95% CI: 1.08-2.05) and hypertension (OR = 1.63; 95% CI: 1.26-2.11).Conclusion: The results of the present study shows that the elevated TyG index is significantly associated with the presence of prehypertension and hypertension in children and adolescents. What is Known: • Prevalence of elevated blood pressure in children and adolescents has been increasing worldwide. • Insulin resistance plays a key role in the pathogenesis of hypertension. What is New: • The elevated TyG index is significantly associated with the presence of prehypertension in children aged 6-9 years and adolescents aged 10-15 years. • The elevated TyG index is significantly associated with the presence of hypertension in children aged 6-9 years and adolescents aged 10-15 years.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.