Evidence map›Paper›PMID 31081515›Full record

ArticleInternational orthopaedics2020

High mortality following distal femur fractures: a cohort study including three hundred and two distal femur fractures.

Peter Larsen, Adriano Axel Ceccotti, Rasmus Elsoe

3 registry-linked trialsAbstract read
PubMed Publisher
In one paragraph

Article in International orthopaedics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 32 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04076735 narecruitingnot on this mapstarted 2021, after this paper: background citation

DIFFIR: Geriatric Distal Femur Fixation Versus Replacement - A Randomized Controlled Trial of Acute Open Reduction Internal Fixation (ORIF) Versus Distal Femoral Replacement (DFR)

TypeinterventionalSponsorUnity Health TorontoRan2021 to 2028Enrolled140ConditionsDistal Femur FractureArmsDistal femoral replacement, Surgical Fixation (ORIF)
NCT05025228 completednot on this map

Analgesic Effect of Paracetamol in Patients With Femur Fracture: is Intravenous Better Than Oral?

TypeobservationalSponsorFondazione Policlinico Universitario Agostino Gemelli IRCCSRan2019 to 2020Enrolled170ConditionsFemur FractureArmsParacetamol
NCT06806839 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Early Weight Bearing in Distal Femoral Fractures, Dual Plating Versus Single Lateral Plating: a Randomized Controlled Study

TypeinterventionalSponsorAssiut UniversityRan2025 to 2027Enrolled34ConditionsDistal Femur FractureArmsdual plating, single plating
3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Clinical outcomes and risk factors in the surgical treatment of distal femur fractures.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026
    Article
  3. Differential complication risks in diabetic and non-diabetic geriatric patients following distal femur fracture surgery.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2026
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. No cost difference between single or dual implants for distal femur fractures in the perioperative period.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2025
    Article
  11. Osteoporotic Distal Femur Fractures: An Overview.Indian journal of orthopaedics · 2025
    Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Distal femur fractures: basic science and international perspectives.OTA international : the open access journal of orthopaedic trauma · 2024
    Article
  17. Article
  18. An analytical model of lateral condylar plate working length.Clinical biomechanics (Bristol, Avon) · 2023
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Peter LarsenDepartment of Occupational Therapy and Physiotherapy, Aalborg University Hospital, Aalborg, Denmark.
Adriano Axel CeccottiDepartment of Orthopaedic Surgery, Aalborg University Hospital, 18-22 Hobrovej, DK-9000, Aalborg, Denmark.
Rasmus ElsoeDepartment of Orthopaedic Surgery, Aalborg University Hospital, 18-22 Hobrovej, DK-9000, Aalborg, Denmark. rae@rn.dk.ORCID http://orcid.org/0000-0001-5781-5604

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWhat are the overall, 30-day, 6-month, and 1-year mortality rates following distal femur fractures?

methodsEpidemiological cohort study. Retrospective reviews of charts and X-rays based on a search in the National Danish Health Registry.

resultsA total of 293 patients were treated for 302 distal femur fractures between 2005 and 2010. The mean age at the time of fracture was 44.0 years for males and 71.6 years for females. The overall mortality rates after a non-periprosthetic distal femur fracture at 30 days, six months, and one year were 5%, 15%, and 21%, respectively. The mortality rates for patients at > 60 years at 30 days, six months, and one year were 8%, 26%, and 35%, respectively. The mortality rates for patients at ≤ 60 years at 30 days, six months, and one year were 1%, 2%, and 3%, respectively. The overall mortality rates after a periprosthetic distal femur fracture at 30 days, six months, and one year were 10%, 15%, and 15%. Males were 2.6 (95% CI 1.01-6.86, P = 0.04) times more likely to die within the first year compared to women. Patients treated by conservative means shows a 2.8 (95% CI 1.41-5.54, P = 0.03) times increased likelihood of death within the first year compared to patients treated with surgery.

conclusionsThe overall one year mortality rate was 21% for non-periprosthetic distal femur fractures and was elevated to 35% in patients older than 60 years. Patients presenting with a periprosthetic fracture showed a one year mortality rate of 15%.

Indexed as

AdolescentAdultAgedAged, 80 and overAge FactorsArthroplasty, Replacement, KneeChildChild, PreschoolComorbidityConservative TreatmentDenmarkFemaleFemoral FracturesFemurFracture FixationHumansDistal femur fracturesMortalityPeriprosthetic fracturesPopulation-based epidemiology

Identifiers

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.