Evidence map›Paper›PMID 31080965›Full record

ArticleFunctional imaging and modeling of the heart : ... International Workshop, FIMH ..., proceedings. FIMH (Conference)2017

Modeling of Myocardium Compressibility and its Impact in Computational Simulations of the Healthy and Infarcted Heart.

Joao S Soares, David S Li, Eric Lai, Joseph H Gorman, Robert C Gorman, Michael S Sacks

Abstract read
In one paragraph

Article in Functional imaging and modeling of the heart : ... International Workshop, FIMH ..., proceedings. FIMH (Conference), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. A Neural Network Finite Element Trileaflet Heart Valve Model Incorporating Multi-Body Contact.International journal for numerical methods in biomedical engineering · 2025
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. A Contemporary Look at Biomechanical Models of Myocardium.Annual review of biomedical engineering · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Joao S SoaresCenter for Computational Simulation, Institute for Computational Engineering and Sciences, University of Texas at Austin, Austin, TX, USA.
David S LiCenter for Computational Simulation, Institute for Computational Engineering and Sciences, University of Texas at Austin, Austin, TX, USA.
Eric LaiGorman Cardiovascular Research Group, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Joseph H GormanGorman Cardiovascular Research Group, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Robert C GormanGorman Cardiovascular Research Group, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Michael S SacksCenter for Computational Simulation, Institute for Computational Engineering and Sciences, University of Texas at Austin, Austin, TX, USA.

Funding

Surgery to Prevent Post Infarction Ventricular RemodelingR01HL063954 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI GORMAN, ROBERT C · 2001 to 2018
$9.8M
Biomechanical Optimization of TE Heart ValvesR01HL068816 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI WAGNER, WILLIAM R · 2002 to 2011
$3.1M
Mechanisms of In-Vivo Remodeling in Tissue Engineered Heart ValvesR01HL089750 · NHLBI · UNIVERSITY OF TEXAS AT AUSTIN · PI SACKS, MICHAEL S · 2007 to 2010
$3.1M
GAGs: Function &Fixation in Bioprosthetic Heart ValvesR01HL070969 · NHLBI · CLEMSON UNIVERSITY · PI SACKS, MICHAEL S, VYAVAHARE, NAREN R · 2003 to 2011
$2.9M
Comprehensive Training Program in Imaging Science and InformaticsT32EB007507 · NIBIB · UNIVERSITY OF TEXAS AT AUSTIN · PI MARKEY, MIA K, RYLANDER, HENRY GRADY · 2009 to 2024
$2.7M
Design and Simulation of Valvular Replacement BiomaterialsR01HL108330 · NHLBI · UNIVERSITY OF TEXAS AT AUSTIN · PI GORMAN, JOSEPH H, SACKS, MICHAEL S · 2012 to 2015
$2.3M
Investigation of the effect of injected hydrogel properties on post-myocardial infarction ventricular remodeling using an integrated experimental-numerical finite element modeling approachF31HL139113 · NHLBI · UNIVERSITY OF TEXAS AT AUSTIN · PI LI, DAVID SHUEN · 2017 to 2020
$119k
NHLBI NIH HHS F31 HL139113NHLBI NIH HHS R01 HL063954NHLBI NIH HHS R01 HL068816NHLBI NIH HHS R01 HL070969NHLBI NIH HHS R01 HL089750NHLBI NIH HHS R01 HL108330NIBIB NIH HHS T32 EB007507
6 · The paper itself

Abstract

Simulation of heart function requires many components, including accurate descriptions of regional mechanical behavior of the normal and infarcted myocardium. Myocardial compressibility has been known for at least two decades, however its experimental measurement and incorporation into compu-tational simulations has not yet been widely utilized in contemporary cardiac models. In the present work, based on novel in-vivo ovine experimental data, we developed a specialized compressible model that reproduces the peculiar unim-odal compressible behavior of myocardium. Such simulations will be extremely valuable to understand etiology and pathophysiology of myocardium remodeling and its impact on tissue-level properties and organ-level cardiac function.

Indexed as

Cardiac simulationCompressibilityMyocardium

Identifiers

PMID31080965
PMCPMC6510496

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.