Evidence map›Paper›PMID 31080951›Full record

ArticleTurkish journal of anaesthesiology and reanimation2019

Influence of a Tourniquet on Opioid Consumption After Local Infiltration Analgesia for Total Knee Arthroplasty.

Sietske M K Bakker, Nienke M Kosse, Sakib Crnic, Gert-Jan Scheffer, Rudolf Stienstra

Abstract read
In one paragraph

Article in Turkish journal of anaesthesiology and reanimation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Tourniquet use for knee replacement surgery.The Cochrane database of systematic reviews · 2020
    Pooled it
  3. Trial
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sietske M K BakkerDepartment of Anaesthesiology and Pain Medicine, Sint Maartenskliniek Nijmegen, The Netherlands.ORCID 0000-0003-4804-8348
Nienke M KosseResearch Department, Sint Maartenskliniek Nijmegen, The Netherlands.ORCID 0000-0001-9532-9359
Sakib CrnicDepartment of Planning, Control and Analysis, Sint Maartenskliniek Nijmegen, The Netherlands.
Gert-Jan SchefferDepartment of Anaesthesiology, Pain and Palliative Care, Radboudumc, Nijmegen, The Netherlands.
Rudolf StienstraDepartment of Anaesthesiology and Pain Medicine, Sint Maartenskliniek Nijmegen, The Netherlands.ORCID 0000-0002-0523-4530

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveLocal infiltration analgesia (LIA) with ropivacaine is increasingly used to provide postoperative analgesia after total knee arthroplasty (TKA). TKA may be performed with or without the use of a tourniquet. The absence of local blood flow when infiltrating local anaesthesia below an inflated tourniquet may affect the rate of systemic absorption, and this may have an effect on the duration and intensity of analgesia as compared with LIA without the use of a tourniquet. The aim of the present study was to investigate the influence of tourniquet use during surgery on the time to first request (TTFR) of opioids and opioid consumption.

methodsTwo historical time-based cohorts (one with and one without tourniquet during surgery) of 300 patients underwent primary TKA under spinal anaesthesia and received LIA to provide postoperative analgesia. The cohorts were compared for TTFR of opioids and opioid consumption.

resultsTTFR did not significantly differ between the tourniquet and non-tourniquet groups with a median (25

conclusionThere was no difference in the time to first opioid consumption, suggesting that the presence of an inflated tourniquet during local anaesthetic injection does not alter systemic absorption sufficiently to affect the duration of analgesia. However, the use of a tourniquet was associated with a higher opioid consumption, which is most likely caused by pain resulting from the tourniquet itself.

Indexed as

Anaestheticsanalgesicsarthroplastykneelocalopioidropivacainetourniquets

Identifiers

PMID31080951
PMCPMC6499046

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.