Evidence map›Paper›PMID 31080923›Full record

ArticleKidney international reports2019

Predialysis Nephrology Care and Incident Atrial Fibrillation in Older Patients With ESKD Initiating Dialysis.

Samaya Anumudu, Medha Airy, Kevin F Erickson, Sankar D Navaneethan, Tara I Chang, Wolfgang C Winkelmayer, Jingbo Niu

Abstract read
In one paragraph

Article in Kidney international reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Samaya AnumuduSection of Nephrology, Department of Medicine, Baylor College of Medicine, Houston, Texas, USA.
Medha AirySection of Nephrology, Department of Medicine, Baylor College of Medicine, Houston, Texas, USA.
Kevin F EricksonSection of Nephrology, Department of Medicine, Baylor College of Medicine, Houston, Texas, USA.
Sankar D NavaneethanSection of Nephrology, Department of Medicine, Baylor College of Medicine, Houston, Texas, USA.
Tara I ChangDivision of Nephrology, Department of Medicine, Stanford University School of Medicine, Palo Alto, California, USA.
Wolfgang C WinkelmayerSection of Nephrology, Department of Medicine, Baylor College of Medicine, Houston, Texas, USA.
Jingbo NiuSection of Nephrology, Department of Medicine, Baylor College of Medicine, Houston, Texas, USA.

Funding

The Atrial Fibrillation - Factor Identification to Risk Modification Study in HDR01DK095024 · NIDDK · STANFORD UNIVERSITY · PI WINKELMAYER, WOLFGANG CHRISTOPH · 2012 to 2023
$4.3M
Towards optimizing care for cardiovascular disease in chronic kidney diseaseK23DK095914 · NIDDK · STANFORD UNIVERSITY · PI CHANG, TARA I-HSIN · 2013 to 2017
$908k
The Effect of Provider Market Competition on Patient Health Outcomes in DialysisK23DK101693 · NIDDK · STANFORD UNIVERSITY · PI ERICKSON, KEVIN · 2014 to 2018
$888k
NIDDK NIH HHS K23 DK095914NIDDK NIH HHS K23 DK101693NIDDK NIH HHS R01 DK095024
6 · The paper itself

Abstract

backgroundAtrial fibrillation (AF) is common in patients with end-stage kidney disease (ESKD) on dialysis. Whether pre-ESKD nephrology care associates with AF is uncertain.

methodsWe conducted a retrospective cohort study of older US patients (≥67 years) with Medicare A&B who initiated dialysis (1996-2013) without a prior diagnosis of AF. Patients were categorized by the duration and number of predialysis nephrology outpatient visits. Patients were followed for 1 year for a new diagnosis of AF. We used multivariable Cox proportional hazards regression while accounting for the competing risks of kidney transplantation and death.

resultsWe identified 316,067 patients with ESKD initiating dialysis between 1996 and 2013 who had no prior AF diagnosis. In this cohort, 66.9% had any pre-ESKD outpatient nephrology care, with the first outpatient nephrology visit before dialysis initiation occurring at ≤6 months in 17.9%, 7 to 12 months in 9.4%, and >12 months in 39.6%. Outpatient pre-ESKD nephrology care for ≤6, 7 to 12, and >12 months versus none yielded adjusted cause-specific hazard ratios (HRs) of 0.87 (95% CI: 0.84-0.89), 0.83 (95% CI: 0.81-0.86), and 0.85 (95% CI: 0.83-0.87) for incident AF, respectively. Further, having 1 to 4 pre-ESKD outpatient nephrology visits, 5 to 9 visits, and ≥10 visits versus none yielded adjusted cause-specific HRs of 0.89 (95% CI: 0.86-0.91), 0.86 (95% CI: 0.83-0.88), and 0.81 (95% CI: 0.79-0.83), respectively.

conclusionsHaving any predialysis nephrology care before initiation of dialysis was associated with slightly lower adjusted rates of incident AF over the first year of dialysis. The optimal timing and intensity of nephrology care to reduce the incidence of AF and other adverse health events requires further study.

Indexed as

arrhythmiaESRDhemodialysisoutcomesperitoneal dialysis

Identifiers

PMID31080923
PMCPMC6506758

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