Evidence map›Paper›PMID 31080921›Full record

ArticleKidney international reports2019

Short-term Changes in Urine Beta 2 Microglobulin Following Recovery of Acute Kidney Injury Resulting From Snake Envenomation.

Challa Jaswanth, P S Priyamvada, Bobby Zachariah, Sathish Haridasan, Sreejith Parameswaran, R P Swaminathan

Open access · goldAbstract read
In one paragraph

Article in Kidney international reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Snake bite associated with acute kidney injury.Pediatric nephrology (Berlin, Germany) · 2021
    Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Challa JaswanthDepartment of Nephrology, Jawaharlal Institute of Post Graduate Medical Education and Research, Puducherry, India.
P S PriyamvadaDepartment of Nephrology, Jawaharlal Institute of Post Graduate Medical Education and Research, Puducherry, India.
Bobby ZachariahDepartment of Biochemistry, Jawaharlal Institute of Post Graduate Medical Education and Research, Puducherry, India.
Sathish HaridasanDepartment of Nephrology, Jawaharlal Institute of Post Graduate Medical Education and Research, Puducherry, India.
Sreejith ParameswaranDepartment of Nephrology, Jawaharlal Institute of Post Graduate Medical Education and Research, Puducherry, India.
R P SwaminathanDepartment of Medicine, Jawaharlal Institute of Post Graduate Medical Education and Research, Puducherry, India.
Jawaharlal Institute of Post Graduate Medical Education and Research · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionUrine β2 microglobulin (β2m) is a validated marker to diagnose sepsis and toxin-related acute kidney injury (AKI). In the current study, we used urine β2m as a potential marker to identify persistent tubular dysfunction following a clinical recovery from snake venom-related AKI.

methodsA total of 42 patients who developed AKI following hemotoxic envenomation were followed up for a period of 6 months. Urine albumin excretion, estimated glomerular filtration rate (eGFR), and urine β2m levels were measured at 2 weeks, 3 months, and 6 months following discharge.

resultsAt the end of 6 months of follow-up, 6 patients (14.3 %) progressed to chronic kidney disease (CKD) (eGFR < 60 ml and/or urine albumin excretion > 30 mg/d). The urine β2m levels were 1590 μg/l (interquartile range [IQR] 425-5260), 610 μg/l (IQR 210-1850), 850 μg/l (IQR 270-2780) at 2 weeks, 3 months, and 6 months, respectively (

conclusionsUrine β2m levels remain persistently elevated in approximately half of the individuals who recover from AKI due to snake envenomation.

Indexed as

acute kidney injurybeta 2 microglobulin

Identifiers

PMID31080921
PMCPMC6506712
OpenAlexW2911571960

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.