Evidence map›Paper›PMID 31080864›Full record

ArticleGynecologic oncology reports2019

NTRK-1 fusion in endocervical fibroblastic malignant peripheral nerve sheath tumor marking eligibility for larotrectinib therapy: A case report.

A E Wells, A M Mallen, M M Bui, D R Reed, S M Apte

Erratum issuedAbstract readCase Reports
In one paragraph

Article in Gynecologic oncology reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. TPM3::NTRK1-rearranged uterine sarcoma: case report and literature review.International journal of clinical and experimental pathology · 2024
    Article
  8. Article
  9. Adult NTRK-rearranged spindle cell neoplasms of the viscera: with an emphasis on rare locations and heterologous elements.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2022
    Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

A E WellsUniversity of South Florida, Morsani College of Medicine, 12901 Bruce B Downs Blvd, Tampa, FL 33612, United States of America.
A M MallenUniversity of South Florida, Department of Gynecologic Oncology, Moffitt Cancer Center, 12902 USF Magnolia Drive, Tampa, FL 33612, United States of America.
M M BuiDepartment of Pathology, Moffitt Cancer Center, 12902 USF Magnolia Drive, Tampa, FL 33612, United States of America.
D R ReedMoffit Cancer Center, Department of Interdisciplinary Cancer Management and Sarcoma Department, 12902 USF Magnolia Drive, Tampa, FL 33612, United States of America.
S M ApteDepartment of Gynecologic Oncology, Moffitt Cancer Center, 12902 USF Magnolia Drive, Tampa, FL 33612, United States of America.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

•<1% of cervical cancers are sarcomas.•Data on neurofibrosarcoma management is scarce.•Larotrectinib is approved for NTRK1 gene fusion tumors without acquired resistance.•Targeted therapy of tumor genes may expand treatment for a rare cervical sarcoma.

Indexed as

Cervical cancerLarotrectinibMalignant peripheral nerve sheath tumorNeurofibrosarcomaNTRK-1Targeted therapy

Identifiers

PMID31080864
PMCPMC6506462

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.