Evidence map›Paper›PMID 31080823›Full record

ArticleBioMed research international2019

Prognostic Nomogram for the Overall Survival of Patients with Newly Diagnosed Multiple Myeloma.

Yue Zhang, Xiao-Lei Chen, Wen-Ming Chen, He-Bing Zhou

Abstract read
In one paragraph

Article in BioMed research international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yue ZhangDepartment of Hematology, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China.ORCID 0000-0002-8017-6596
Xiao-Lei ChenDepartment of Hematology, Beijing Luhe Hospital, Capital Medical University, Beijing, China.
Wen-Ming ChenDepartment of Hematology, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China.ORCID 0000-0001-9070-9280
He-Bing ZhouDepartment of Hematology, Beijing Luhe Hospital, Capital Medical University, Beijing, China.ORCID 0000-0002-7486-7585

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To establish a nomogram for predicting the overall survival (OS) of patients with newly diagnosed multiple myeloma (MM), 304 patients with newly diagnosed MM were recruited between June 1, 2010, and June 30, 2015, from the Beijing Chaoyang Hospital, Capital Medical University, and randomly divided into training (n=214) and validation (n=90) cohorts. The Kaplan-Meier method and the Cox proportional hazards regression model were used to evaluate the prognostic effects of multiple clinical and laboratory parameters on survival. Significant prognostic factors were combined to build a nomogram. The discriminative ability and predictive accuracy of the nomogram were evaluated using the index of concordance (C-index) and calibration curves and compared with the five staging systems currently used for MM. Multivariate analysis of the training cohort revealed that the age at diagnosis, clonal bone marrow plasma cells, serum lactate dehydrogenase, serum

Indexed as

AdultAgedAged, 80 and overCohort StudiesFemaleHumansKaplan-Meier EstimateMaleMiddle AgedMultiple MyelomaNeoplasm StagingNomogramsPrognosisProportional Hazards Models

Identifiers

PMID31080823
PMCPMC6476154

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.