Evidence map›Paper›PMID 31080698›Full record

ArticleInternal medicine: open access2018

Non-invasive Imaging Methods for Brown Adipose Tissue Detection and Function Evaluation.

Yaqi Zhang, Xiaofei Hu, Su Hu, Alessandro Scotti, Kejia Cai, Jian Wang, Xin Zhou, Ding Yang, Matteo Figini, Liang Pan and 3 more

Open access · greenAbstract read
In one paragraph

Article in Internal medicine: open access, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Molecular Imaging of Brown Adipose Tissue Mass.International journal of molecular sciences · 2021
    Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 2 countries.

Yaqi ZhangDepartment of Obstetrics and Gynecology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Xiaofei HuDepartment of Radiology, Third Military Medical University Southwest Hospital, Chongqing, China.
Su HuDepartment of Radiology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.
Alessandro ScottiDepartment of Radiology, University of Illinois at Chicago, Chicago, IL, USA.
Kejia CaiDepartment of Radiology, University of Illinois at Chicago, Chicago, IL, USA.
Jian WangDepartment of Radiology, Third Military Medical University Southwest Hospital, Chongqing, China.
Xin ZhouDepartment of Cardiology, Pingjin Hospital, Tianjin, China.
Ding YangDepartment of Biomedical Engineering, University of Florida, Gainesville, FL, USA.
Matteo FiginiDepartment of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Liang PanDepartment of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Junjie ShangguanDepartment of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Jia YangDepartment of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Zhuoli ZhangDepartment of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Northwestern University · USArmy Medical University · CNUniversity of Illinois Chicago · USFirst Affiliated Hospital of Soochow University · CNUniversity of Florida · US

Funding

MRI-Guided Dendritic-Cell-Based Vaccine Immunotherapy for Pancreatic CancerR01CA209886 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI Vahid Yaghmai, Zhuoli Zhang · 2016 to 2026
$3.3M
MRI-Guided Irreversible Electroporation Ablation for Liver TumorsR01CA196967 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI ZHANG, ZHUOLI · 2015 to 2018
$1.4M
NCI NIH HHS R01 CA196967NCI NIH HHS R01 CA209886
6 · The paper itself

Abstract

Brown Adipose Tissue (BAT) has a major role in thermoregulation, producing heat by non-shivering thermogenesis. Primarily found in animals and human infants, the presence of significant brown adipose tissue was identified only recently, and its metabolic role in adults was reconsidered. BAT is believed to have an important role in many metabolic diseases, such as obesity and diabetes, and also to be associated with cancer cachexia. Therefore, it is currently a topic of great interest in the research community, and many groups are investigating the mechanisms underlying BAT metabolism in normal and pathological conditions. However, well established non-invasive methods for assessing BAT distribution and function are still lacking. The purpose of this review is to summarize the current state of the art of these methods, with a particular focus on PET, CT and MRI.

Indexed as

Brown adipose tissueImagingMagnetic resonancePositron emission tomographyThermogenesis

Identifiers

PMID31080698
PMCPMC6508884
OpenAlexW2914978962

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.