Evidence map›Paper›PMID 31080608›Full record

ArticleUnited European gastroenterology journal2019

Reduction of multitasking distractions underlies the higher adenoma detection rate of water exchange compared to air insufflation - blinded analysis of withdrawal phase videos.

Yu-Hsi Hsieh, Malcolm Koo, Chih-Wei Tseng, Hsiu-Wen Yang, Felix W Leung

Registry-linked trialAbstract read
In one paragraph

Article in United European gastroenterology journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07456007 (A Patient Blinded, Randomized, Controlled Trial Comparing Right Colon Adenoma Detection Rate in Colonoscopy Using Right Colon Water Exchange and Traditional Air Insufflation), which is not on this map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07456007 nacompletednot on this mapstarted 2020, after this paper: background citation

A Patient Blinded, Randomized, Controlled Trial Comparing Right Colon Adenoma Detection Rate in Colonoscopy Using Right Colon Water Exchange and Traditional Air Insufflation

TypeinterventionalSponsorDalin Tzu Chi General HospitalRan2020 to 2026Enrolled414ConditionsRight Colon Adenoma Detectation Rate, Water Exchange ColonoscopyArmsRight colon water exchange, Air nsufflation
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Water Exchange Improves Detection of Advanced Colorectal Neoplasia: Pooled Analysis of Four Randomized Trials.JGH open : an open access journal of gastroenterology and hepatology · 2026
    Article
  5. Computer-Aided Detection False Positives in Colonoscopy.Diagnostics (Basel, Switzerland) · 2021
    Review
  6. Water assistance: also for sigmoidoscopy?Endoscopy international open · 2020
    Article
  7. Observational
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yu-Hsi HsiehDivision of Gastroenterology, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Chiayi, Taiwan.
Malcolm KooGraduate Institute of Long-term Care, Tzu Chi University of Science and Technology, Hualien, Taiwan.
Chih-Wei TsengDivision of Gastroenterology, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Chiayi, Taiwan.ORCID 0000-0002-6951-4646
Hsiu-Wen YangDivision of Gastroenterology, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Chiayi, Taiwan.
Felix W LeungSepulveda Ambulatory Care Center, Veterans Affairs Greater Los Angeles Healthcare System, North Hill, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Experts have hypothesized that a reduction of multitasking distractions and improved bowel cleanliness can explain why insertion water exchange enhances adenoma detection rate. Objective: The purpose of this study was to test the role of both distractions during withdrawal and bowel cleanliness in enhancing adenoma detection rate using coded video records of colonoscopy. Methods: The withdrawal phase of videos of 299 consecutive colonoscopies from two randomized controlled trials comparing water exchange versus air insufflation at a regional hospital in Taiwan were coded. The primary outcome was distractions; activities that preclude full attention being paid to inspection of the mucosa for polyps. A single blinded reviewer collected the data. Results: There were significant agreements in inter-rater reliability indexes. Compared to air insufflation, water exchange had significantly fewer distractions; higher diagnostic yield (intervention time and number), adenoma detection rate, and Boston Bowel Preparation Scale score. Water exchange had a higher withdrawal technique score (predominantly adequacy of cleaning). The association between increased adenoma detection rate and water exchange was mediated by the number of distractions and withdrawal time, but not the Boston Bowel Preparation Scale score. Conclusion: The speculation by experts that a reduction of multitasking distractions underlies the significantly higher adenoma detection rate of water exchange is supported by the current study. Increased bowel cleanliness did not contribute to the increased adenoma detection rate by use of water exchange.

Indexed as

ColonoscopyInsufflationAdenomaAdultAgedAirColorectal NeoplasmsFemaleHumansMaleMiddle AgedVideo RecordingWaterYoung AdultWateradenomaColonoscopydistractionwater exchange

Identifiers

PMID31080608
PMCPMC6498805

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.