Evidence map›Paper›PMID 31080606›Full record

ArticleUnited European gastroenterology journal2019

Radiofrequency ablation for patients with refractory symptomatic anaemia secondary to gastric antral vascular ectasia.

Cormac Magee, Gideon Lipman, Durayd Alzoubaidi, Martin Everson, Rami Sweis, Matthew Banks, David Graham, Charles Gordon, Laurence Lovat, Charles Murray and 1 more

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in United European gastroenterology journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06830317 (A Multicenter, Observational, Prospective Study on the Efficacy of Endoscopic Radiofrequency Treatment in Reducing the Need for Blood Transfusions Compared with Conventional Therapies in Patients with Gastric Antral Vascular Ectasia), which is not on this map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06830317 not yet recruitingnot on this mapstarted 2025, after this paper: background citation

A Multicenter, Observational, Prospective Study on the Efficacy of Endoscopic Radiofrequency Treatment in Reducing the Need for Blood Transfusions Compared with Conventional Therapies in Patients with Gastric Antral Vascular Ectasia (GAVE)

TypeobservationalSponsorAzienda Ospedaliera Specializzata in Gastroenterologia Saverio de BellisRan2025 to 2027Enrolled80ConditionsGAVE - Gastric Antral Vascular EctasiaArmsEndoscopic Radiofrequency treatment, QoL EQ5D questionaire
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. The Use of Expert Elicitation among Computational Modeling Studies in Health Research: A Systematic Review.Medical decision making : an international journal of the Society for Medical Decision Making · 2022
    Pooled it
  2. Review
  3. Review
  4. Gastric Antral Vascular Ectasia in Limited Systemic Sclerosis.The Brown journal of hospital medicine · 2022
    Article
  5. Article
  6. Endoscopic treatment for gastric antral vascular ectasia.Therapeutic advances in chronic disease · 2021
    Review
  7. Article
  8. Radiological findings in gastrointestinal scleroderma.Journal of scleroderma and related disorders · 2020
    Review
  9. Setting the stage for research in endoscopy.United European gastroenterology journal · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Cormac MageeUniversity College London Hospital, London, UK.
Gideon LipmanUniversity College London Hospital, London, UK.
Durayd AlzoubaidiUniversity College London Hospital, London, UK.
Martin EversonUniversity College London Hospital, London, UK.
Rami SweisUniversity College London Hospital, London, UK.
Matthew BanksUniversity College London Hospital, London, UK.
David GrahamUniversity College London Hospital, London, UK.
Charles GordonRoyal Bournemouth and Christchurch Hospital, Bournemouth, UK.
Laurence LovatUniversity College London Hospital, London, UK.
Charles MurrayUniversity College London Hospital, London, UK.
Rehan HaidryUniversity College London Hospital, London, UK.
University College Hospital · GBRoyal Bournemouth Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Gastric antral vascular ectasia (GAVE) is a rare cause of gastrointestinal bleeding, often causing iron deficiency anaemia. Previous studies have looked at the management of this with argon plasma coagulation, laser therapy and endoscopic band ligation. Methods: This was a single-centre prospective study to evaluate the efficacy and safety of radiofrequency ablation (RFA) in patients with GAVE with persistent anaemia refractory to at least one session of first-line endoscopic therapy. Patients were treated with a through-the-scope (TTS) radiofrequency catheter at two endoscopic sessions six weeks apart. The primary outcome was change in haemoglobin at six months posttreatment. The secondary outcomes were reduction in blood or iron requirements, endoscopic surface area regression and complications. Results: Twenty patients were treated. The mean change in haemoglobin at six months was +12.6 g/l (95% confidence interval 11.7-24.3 g/l), paired Discussion: This small study suggests that RFA is a safe and effective treatment for GAVE. Our study uses the TTS catheter compared to other studies, and demonstrates prolonged improvement in haemoglobin and reduction in blood and iron requirements with a novel assessment of surface area regression.

Indexed as

Radiofrequency AblationAgedAged, 80 and overAnemia, RefractoryFemaleGastric Antral Vascular EctasiaGastrointestinal HemorrhageGastroscopyHumansMaleMiddle AgedTime FactorsTreatment OutcomeEndoscopygastric antral vascular ectasiagastrointestinal bleedingradiofrequency ablation

Identifiers

PMID31080606
PMCPMC6498795
OpenAlexW2900452273

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.