Evidence map›Paper›PMID 31080480›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2019

Protective Effect of the Total Triterpenes of

Wei Huang, Hui Ding, Lu-Yao Chen, Lin Ni, Yi-Fang Ruan, Xiao-Xing Zou, Min Ye, Shuang-Quan Zou

Open access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Wei HuangCollege of Life Sciences, Fujian Agriculture and Forestry University, Fuzhou 350002, China.ORCID 0000-0002-9856-4888
Hui DingEngineering Research Institute of Conservation, Utilization of Natural Bioresources, Fujian Agriculture and Forestry University, Fuzhou 350002, China.
Lu-Yao ChenEngineering Research Institute of Conservation, Utilization of Natural Bioresources, Fujian Agriculture and Forestry University, Fuzhou 350002, China.
Lin NiEngineering Research Institute of Conservation, Utilization of Natural Bioresources, Fujian Agriculture and Forestry University, Fuzhou 350002, China.ORCID 0000-0001-6118-6724
Yi-Fang RuanFujian Key Laboratory of Natural Medicine Pharmacology, School of Pharmacy, Fujian Medical University, Fuzhou 350004, China.
Xiao-Xing ZouEngineering Research Institute of Conservation, Utilization of Natural Bioresources, Fujian Agriculture and Forestry University, Fuzhou 350002, China.
Min YeFujian Key Laboratory of Natural Medicine Pharmacology, School of Pharmacy, Fujian Medical University, Fuzhou 350004, China.ORCID 0000-0001-7451-6542
Shuang-Quan ZouEngineering Research Institute of Conservation, Utilization of Natural Bioresources, Fujian Agriculture and Forestry University, Fuzhou 350002, China.ORCID 0000-0002-4125-7916
Fujian Agriculture and Forestry University · CNFujian Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLiver injury has been recognized as a primary cause of hepatic morbidity and mortality.

objectiveThe main aim of the study was to investigate the constituent and potential hepatoprotective mechanism of the total triterpenes of

methodsThe constituent of TTEP was analyzed by a series of silica gel column to get single compounds and then identified by NMR and MS.

results8 pentacyclic triterpene acids were separated and identified by NMR and MS. TTEP treatment (50, 100, and 200 mg/Kg) improved the immune function of the BCG/LPS-infected mice, dose-dependently alleviated the BCG/LPS-induced inflammation and oxidative stress, and ameliorated the hepatocyte apoptosis in the liver tissue.

conclusionThe pericarp of

Identifiers

PMID31080480
PMCPMC6475556
OpenAlexW2925564840

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.