Evidence map›Paper›PMID 31080170›Full record

ArticleThe Journal of biological chemistry2019

Synthesis of oxidized phospholipids by

Gao-Yuan Liu, Sung Ho Moon, Christopher M Jenkins, Harold F Sims, Shaoping Guan, Richard W Gross

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
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  14. The Biosynthesis of Enzymatically Oxidized Lipids.Frontiers in endocrinology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 3 countries.

Gao-Yuan LiuFrom the Department of Chemistry, Washington University, Saint Louis, Missouri 63130 and.
Sung Ho MoonDivision of Bioorganic Chemistry and Molecular Pharmacology, Department of Medicine.
Christopher M JenkinsDivision of Bioorganic Chemistry and Molecular Pharmacology, Department of Medicine.
Harold F SimsDivision of Bioorganic Chemistry and Molecular Pharmacology, Department of Medicine.
Shaoping GuanDivision of Bioorganic Chemistry and Molecular Pharmacology, Department of Medicine.
Richard W GrossFrom the Department of Chemistry, Washington University, Saint Louis, Missouri 63130 and rgross@wustl.edu.
Institute of Bioorganic Chemistry · BYInstitute of Developmental Physiology · RU

Funding

Washington University Nutrition Obesity Research CenterP30DK056341 · NIDDK · WASHINGTON UNIVERSITY · PI Dominic N Reeds · 1999 to 2026
$30.2M
REGULATION OF MYOCARDIAL PHOSPHOLIPASES AND LIPASES IN DIABETIC MYOCARDIUMR01HL118639 · NHLBI · WASHINGTON UNIVERSITY · PI GROSS, RICHARD W · 2013 to 2025
$9.1M
NOVEL LIPID 2ND MESSENGERS REGULATING BIOENERGETICS AND SIGNALING IN HUMAN MYOCARDIUMR01HL133178 · NHLBI · WASHINGTON UNIVERSITY · PI GROSS, RICHARD W · 2016 to 2024
$3.8M
NHLBI NIH HHS R01 HL118639NHLBI NIH HHS R01 HL133178NIDDK NIH HHS P30 DK056341
6 · The paper itself

Abstract

Recently, oxidized phospholipid species have emerged as important signaling lipids in activated immune cells and platelets. The canonical pathway for the synthesis of oxidized phospholipids is through the release of arachidonic acid by cytosolic phospholipase A

Indexed as

AcylationAcyltransferasesAnimalsBlood PlateletsHydroxyeicosatetraenoic AcidsLysophospholipidsMiceMicrosomes, LiverOxidation-ReductionPhospholipasesPhospholipidsSubstrate Specificity15-hydroxy-5,8,11,13-eicosatetraenoic acidAcyltransferasesHydroxyeicosatetraenoic AcidsLysophospholipidsPhospholipasesPhospholipidsacyltransferaselipid metabolismlipidomicslipid peroxidationlipid synthesislysophospholipidmass spectrometry (MS)oxidized lysophospholipidoxidized phospholipidphospholipase Aphospholipidsn-1 acyltransferasestereoselectivity

Identifiers

PMID31080170
PMCPMC6664186
OpenAlexW2946024917

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.