Evidence map›Paper›PMID 31080143›Full record

ReviewPain management nursing : official journal of the American Society of Pain Management Nurses2019

The Influence of Race, Ethnicity and Genetic Variants on Postoperative Pain Intensity: An Integrative Literature Review.

Mallory Perry, Kyle Baumbauer, Erin E Young, Susan G Dorsey, Jacquelyn Y Taylor, Angela R Starkweather

Open access · greenAbstract readReview
In one paragraph

Review in Pain management nursing : official journal of the American Society of Pain Management Nurses, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it, 54 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Do Diabetes and Genetic Polymorphisms in theJournal of clinical medicine · 2025
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
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  11. Are There Racial Disparities in Perioperative Pain? A Retrospective Study of a Gynecological Surgery Cohort.Journal of perianesthesia nursing : official journal of the American Society of PeriAnesthesia Nurses · 2024
    Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Mallory PerryUniversity of Connecticut School of Nursing, Storrs, Connecticut. Electronic address: Mallory.perry@uconn.edu.
Kyle BaumbauerUniversity of Connecticut School of Nursing, Storrs, Connecticut; UConn Health, Department of Neuroscience, Farmington, Connecticut.
Erin E YoungUniversity of Connecticut School of Nursing, Storrs, Connecticut; UConn Health, Department of Genetics and Genome Sciences, Farmington, Connecticut.
Susan G DorseyUniversity of Maryland School of Nursing, Baltimore, Maryland.
Jacquelyn Y TaylorNew York University, Rory Meyers College of Nursing, New York, New York.
Angela R StarkweatherUniversity of Connecticut School of Nursing, Storrs, Connecticut.
University of Connecticut · USNew York University · USUConn Health · USUniversity of Maryland, Baltimore · US

Funding

Intergenerational Impact of Genetic and Psychological Factors on Blood PressureR01NR013520 · NINR · YALE UNIVERSITY · PI TAYLOR, JACQUELYN Y · 2014 to 2019
$3.9M
NINR NIH HHS R01 NR013520
6 · The paper itself

Abstract

objectivesChronic postsurgical pain is pain that develops and persists for at least 3 months after a surgical procedure. The purpose of this review was to discover what evidence exists regarding the influence of race and ethnicity on postoperative pain intensity and what evidence exists regarding the influence of genetic polymorphisms on postoperative pain intensity.

designIntegrative literature review. DATA SOURCES: CINAHL, PsychInfo, SCOPUS, and PubMed/Medline databases were searched for entries within the last 10 years. Sources included primary research investigating the relationship among race, ethnicity, and genetics in postoperative pain outcomes. REVIEW/ANALYSIS

methodsStudies adhered to a strict inclusion and exclusion criteria. Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines were utilized to evaluate and assess manuscripts for inclusion.

resultsTwelve manuscripts were included for final review. There are significantly higher preoperative and postoperative pain intensity scores reported between African American and Hispanic individuals compared with non-Hispanic whites. Although some studies identified that non-Hispanic whites consumed more opioids and reported increased pain, there were no significant differences in opioid requirements in Hispanic and non-Hispanic individuals. COMT and OPRM1 were the most identified genetic polymorphisms associated with postoperative pain intensity.

conclusionsThe literature varies with respect to race, ethnicity, and postoperative pain perception. Perioperative pain intensity has been suggested as a significant predictor of chronic postsurgical pain. COMT and OPRM1 may be associated with higher pain perception after surgical procedures.

Indexed as

Black or African AmericanBlack PeopleEthnicityGenetic VariationHispanic or LatinoHumansPain MeasurementPostoperative PainRacial GroupsWhite People

Identifiers

PMID31080143
PMCPMC7841600
OpenAlexW2944720749

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.