Evidence map›Paper›PMID 31079484›Full record

ArticleExperimental biology and medicine (Maywood, N.J.)2019

Whole-exome sequencing indicates

Gabriela Queila de Carvalho-Siqueira, Galina Ananina, Bruno Batista de Souza, Murilo Guimarães Borges, Mirta Tomie Ito, Sueli Matilde da Silva-Costa, Igor de Farias Domingos, Diego Arruda Falcão, Iscia Lopes-Cendes, Marcos André Cavalcanti Bezerra and 6 more

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Experimental biology and medicine (Maywood, N.J.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 2 pooled it
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 syntheses or guidelines pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Interventions for treating leg ulcers in people with sickle cell disease.The Cochrane database of systematic reviews · 2021
    Pooled it
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 1 country.

Gabriela Queila de Carvalho-Siqueira1 Center for Molecular Biology and Genetic Engineering (CBMEG), University of Campinas, Campinas, SP 13083-875, Brazil.
Galina Ananina1 Center for Molecular Biology and Genetic Engineering (CBMEG), University of Campinas, Campinas, SP 13083-875, Brazil.
Bruno Batista de Souza1 Center for Molecular Biology and Genetic Engineering (CBMEG), University of Campinas, Campinas, SP 13083-875, Brazil.
Murilo Guimarães Borges2 Department of Medical Genetics and Genome Medicine, Faculty of Medical Sciences, University of Campinas, Campinas, SP 13083-887, Brazil.ORCID 0000-0002-9854-5783
Mirta Tomie Ito1 Center for Molecular Biology and Genetic Engineering (CBMEG), University of Campinas, Campinas, SP 13083-875, Brazil.
Sueli Matilde da Silva-Costa1 Center for Molecular Biology and Genetic Engineering (CBMEG), University of Campinas, Campinas, SP 13083-875, Brazil.
Igor de Farias Domingos3 Genetics Postgraduate Program, Federal University of Pernambuco, Recife, PE 50670-901, Brazil.
Diego Arruda Falcão3 Genetics Postgraduate Program, Federal University of Pernambuco, Recife, PE 50670-901, Brazil.
Iscia Lopes-Cendes2 Department of Medical Genetics and Genome Medicine, Faculty of Medical Sciences, University of Campinas, Campinas, SP 13083-887, Brazil.
Marcos André Cavalcanti Bezerra3 Genetics Postgraduate Program, Federal University of Pernambuco, Recife, PE 50670-901, Brazil.
Aderson da Silva Araújo4 Hematology and Hemotherapy Foundation of Pernambuco, Recife, PE 52011-000, Brazil.
Antônio Roberto Lucena-Araújo3 Genetics Postgraduate Program, Federal University of Pernambuco, Recife, PE 50670-901, Brazil.
Marilda de Souza Gonçalves5 Gonçalo Moniz Institute (Fiocruz), Salvador, BA 40296-710, Brazil.
Sara Teresinha Olalla Saad6 Hematology and Hemotherapy Center, University of Campinas, Campinas, SP 13083-878, Brazil.
Fernando Ferreira Costa6 Hematology and Hemotherapy Center, University of Campinas, Campinas, SP 13083-878, Brazil.
Mônica Barbosa de Melo1 Center for Molecular Biology and Genetic Engineering (CBMEG), University of Campinas, Campinas, SP 13083-875, Brazil.ORCID 0000-0002-1801-5441
Universidade Estadual de Campinas (UNICAMP) · BRUniversidade Federal de Pernambuco · BRFundação Hemopa · BRFundação Oswaldo Cruz · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdultAnemia, Sickle CellBrazilCase-Control StudiesCohort StudiesExome SequencingFemaleFilaggrin ProteinsGenetic Predisposition to DiseaseGenetic VariationGenotypeHumansInflammationLeg UlcerMaleMiddle AgedFilaggrin ProteinsFLG2 protein, humanS100 Proteinsassociation studycomplex diseaseleg ulcerSickle cell anemiavariantswhole-exome sequencing

Identifiers

PMID31079484
PMCPMC6690137
OpenAlexW2946148918

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.