Evidence map›Paper›PMID 31079030›Full record

ArticleColloids and surfaces. B, Biointerfaces2019

Engineering functional hydrogel microparticle interfaces by controlled oxygen-inhibited photopolymerization.

Daniel Debroy, Katie Dongmei Li-Oakey, John Oakey

Open access · greenAbstract read
In one paragraph

Article in Colloids and surfaces. B, Biointerfaces, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Daniel DebroyDepartment of Chemical Engineering, University of Wyoming, Laramie, WY 82071, United States.
Katie Dongmei Li-OakeyDepartment of Chemical Engineering, University of Wyoming, Laramie, WY 82071, United States. Electronic address: dli1@uwyo.edu.
John OakeyDepartment of Chemical Engineering, University of Wyoming, Laramie, WY 82071, United States. Electronic address: joakey@uwyo.edu.
University of Wyoming · US

Funding

Wyoming INBRE Phase 4- Equipment Supplement for x-ray diffractometer for Center for Advanced Scientific InstrumentationP20GM103432 · NIGMS · UNIVERSITY OF WYOMING · PI Robert Scott Seville · 2012 to 2026
$56.8M
Zebrafish Models of CNS Injury and Locomotor RecoveryP20GM121310 · NIGMS · UNIVERSITY OF WYOMING · PI Rammohan Shukla · 2017 to 2026
$27.2M
NIGMS NIH HHS P20 GM103432NIGMS NIH HHS P20 GM121310
6 · The paper itself

Abstract

Functional poly(ethylene glycol) diacrylate (PEGDA) hydrogel microparticles for the detection of bioactive macromolecules were fabricated via oxygen-inhibited photopolymerization in a droplet microfluidic device. Hydrogel network functionalization and architecture were characterized using a biotin-avidin binding assay, which revealed radial network inhomogeneities dependent on exposure conditions. Empirical results were corroborated using a reaction-diffusion model, describing the effects of exposure intensity on the spatial photopolymerization kinetics and resulting polymeric mesh network. The combination of finely controlled exposure conditions and predictive simulations enables the generation of tailored particles with microengineered interfaces and gradients in crosslinking density, which dictate solute diffusivity and elasticity, augmenting the utility of this approach in engineering multifunctional, size-excluding hydrogel particles for multiplexed biomolecular sensing.

Indexed as

LightMicrospheresPolymerizationAvidinBiotinDiffusionFluorescenceHydrogelsOxygenRhodaminesTissue EngineeringAvidinBiotinHydrogelsneutravidinOxygenRhodaminesBiosensorDropletHydrogel microsphereImmunoassayMicrofluidicsMicrogelPolyethylene glycolPolyethylene glycol diacrylate

Identifiers

PMID31079030
PMCPMC6591085
OpenAlexW2943813251

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.