Evidence map›Paper›PMID 31078876›Full record

ReviewEnvironment international2019

Carcinogenicity assessment: Addressing the challenges of cancer and chemicals in the environment.

Federica Madia, Andrew Worth, Maurice Whelan, Raffaella Corvi

Open access · goldAbstract readReview
In one paragraph

Review in Environment international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 2 pooled it
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 2 syntheses or guidelines pooled it, 115 citations in OpenAlex.

  1. Guideline
  2. Guideline
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Current status and perspectives in environmental oncology.Chronic diseases and translational medicine · 2024
    Article
  13. Article
  14. Natural Compounds for Preventing Age-Related Diseases and Cancers.International journal of molecular sciences · 2024
    Review
  15. Article
  16. Article
  17. Article
  18. Chemical carcinogens: implications for cancer treatment.The Journal of clinical investigation · 2023
    Article
  19. After a Century of Research into Environmental Mutagens and Carcinogens, Where Do We Stand?International journal of environmental research and public health · 2023
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 3 countries.

Federica MadiaEuropean Commission, Joint Research Centre (JRC), Ispra, Italy. Electronic address: federica.madia@ec.europa.eu.
Andrew WorthEuropean Commission, Joint Research Centre (JRC), Ispra, Italy.
Maurice WhelanEuropean Commission, Joint Research Centre (JRC), Ispra, Italy.
Raffaella CorviEuropean Commission, Joint Research Centre (JRC), Ispra, Italy.
Joint Research Centre · ITEuropean Commission · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer is a key public health concern, being the second leading cause of worldwide morbidity and mortality after cardiovascular diseases. At the global level, cancer prevalence, incidence and mortality rates are increasing. These trends are not fully explained by a growing and ageing population: with marked regional and socioeconomic disparities, lifestyle factors, the resources dedicated to preventive medicine, and the occupational and environmental control of hazardous chemicals all playing a role. While it is difficult to establish the contribution of chemical exposure to the societal burden of cancer, a number of measures can be taken to better assess the carcinogenic properties of chemicals and manage their risks. This paper discusses how these measures can be informed not only by the traditional data streams of regulatory toxicology, but also by using new toxicological assessment methods, along with indicators of public health status based on biomonitoring. These diverse evidence streams have the potential to form the basis of an integrated and more effective approach to cancer prevention.

Indexed as

AnimalsCarcinogenesisCarcinogenicity TestsCarcinogensEnvironmental ExposureEnvironmental MonitoringHazardous SubstancesHumansMicePublic HealthRatsCarcinogensHazardous SubstancesCancer riskCarcinogenicity testingChemical exposureEnvironmental healthREACH

Identifiers

PMID31078876
PMCPMC6520474
OpenAlexW2943914335

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.